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j.jstrokecerebrovasdis.2015.04.026.pdf512.53 kBAdobe PDF見る/開く
タイトル: Apparent Diffusion Coefficient and Transient Neurological Deficit after Revascularization Surgery in Moyamoya Disease.
著者: Araki, Yoshio
Takagi, Yasushi
Fushimi, Yasutaka  kyouindb  KAKEN_id  orcid https://orcid.org/0000-0002-1982-3168 (unconfirmed)
Arakawa, Yoshiki  kyouindb  KAKEN_id  orcid https://orcid.org/0000-0003-4626-4645 (unconfirmed)
Funaki, Takeshi  kyouindb  KAKEN_id  orcid https://orcid.org/0000-0001-9489-7469 (unconfirmed)
Kikuchi, Takayuki  kyouindb  KAKEN_id
Takahashi, Jun C
Togashi, Kaori
Miyamoto, Susumu
著者名の別形: 荒木, 芳生
キーワード: Adult
diffusion
moyamoya disease
revascularization surgery
transient neurological deficit
発行日: Sep-2015
出版者: Elsevier Inc.
誌名: Journal of stroke and cerebrovascular diseases
巻: 24
号: 9
開始ページ: 2054
終了ページ: 2059
抄録: 【Background】Transient neurological deficits are relatively common after direct revascularization surgery for moyamoya disease (MMD). Although recent evidence has revealed the clinical features and pathophysiology, preoperative predictors have remained unclear. This study investigated whether the apparent diffusion coefficient (ADC) in normal-appearing white matter (NAWM) on magnetic resonance imaging could offer a predictor of postoperative transient neurological deficits. 【Methods】This study included adult patients with MMD who underwent superficial temporal artery-middle cerebral artery bypass. Preoperative ADCs were measured in NAWM on ipsilateral hemisphere. Single photon emission computed tomography (SPECT) with123I-iodoamphetamine was performed on postoperative days 2-6. Relationships between mean ADC and postoperative transient neurological deficits were assessed. 【Results】Results Twenty of the 26 subjects (76.9%) experienced transient neurological deficits. Focal hyperemia on postoperative SPECT appeared in 11 of the 20 subjects with postoperative transient neurological deficits and 1 of the 6 subjects without (P = .12). Mean ADCs in patients with and without postoperative transient neurological deficits were 748.3 ± 12 mm2/second × 10−6 and 679.7 ± 21.9 mm2/second × 10−6, respectively (P = .0091). 【Conclusions】Preoperative ADC elevation in NAWM may indicate postoperative transient neurological deficits not only in patients with postoperative hyperemia on SPECT, but also in patients with this pathology.
記述: Available online 10 July 2015
著作権等: © 2015. This manuscript version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/
The full-text file will be made open to the public on 10 July 2016 in accordance with publisher's 'Terms and Conditions for Self-Archiving'.
この論文は出版社版でありません。引用の際には出版社版をご確認ご利用ください。
This is not the published version. Please cite only the published version.
URI: http://hdl.handle.net/2433/202246
DOI(出版社版): 10.1016/j.jstrokecerebrovasdis.2015.04.026
PubMed ID: 26166418
出現コレクション:学術雑誌掲載論文等

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