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j.jstrokecerebrovasdis.2015.04.026.pdf | 512.53 kB | Adobe PDF | 見る/開く |
タイトル: | Apparent Diffusion Coefficient and Transient Neurological Deficit after Revascularization Surgery in Moyamoya Disease. |
著者: | Araki, Yoshio Takagi, Yasushi Fushimi, Yasutaka https://orcid.org/0000-0002-1982-3168 (unconfirmed) Arakawa, Yoshiki https://orcid.org/0000-0003-4626-4645 (unconfirmed) Funaki, Takeshi https://orcid.org/0000-0001-9489-7469 (unconfirmed) Kikuchi, Takayuki Takahashi, Jun C Togashi, Kaori Miyamoto, Susumu |
著者名の別形: | 荒木, 芳生 |
キーワード: | Adult diffusion moyamoya disease revascularization surgery transient neurological deficit |
発行日: | Sep-2015 |
出版者: | Elsevier Inc. |
誌名: | Journal of stroke and cerebrovascular diseases |
巻: | 24 |
号: | 9 |
開始ページ: | 2054 |
終了ページ: | 2059 |
抄録: | 【Background】Transient neurological deficits are relatively common after direct revascularization surgery for moyamoya disease (MMD). Although recent evidence has revealed the clinical features and pathophysiology, preoperative predictors have remained unclear. This study investigated whether the apparent diffusion coefficient (ADC) in normal-appearing white matter (NAWM) on magnetic resonance imaging could offer a predictor of postoperative transient neurological deficits. 【Methods】This study included adult patients with MMD who underwent superficial temporal artery-middle cerebral artery bypass. Preoperative ADCs were measured in NAWM on ipsilateral hemisphere. Single photon emission computed tomography (SPECT) with123I-iodoamphetamine was performed on postoperative days 2-6. Relationships between mean ADC and postoperative transient neurological deficits were assessed. 【Results】Results Twenty of the 26 subjects (76.9%) experienced transient neurological deficits. Focal hyperemia on postoperative SPECT appeared in 11 of the 20 subjects with postoperative transient neurological deficits and 1 of the 6 subjects without (P = .12). Mean ADCs in patients with and without postoperative transient neurological deficits were 748.3 ± 12 mm2/second × 10−6 and 679.7 ± 21.9 mm2/second × 10−6, respectively (P = .0091). 【Conclusions】Preoperative ADC elevation in NAWM may indicate postoperative transient neurological deficits not only in patients with postoperative hyperemia on SPECT, but also in patients with this pathology. |
記述: | Available online 10 July 2015 |
著作権等: | © 2015. This manuscript version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/ The full-text file will be made open to the public on 10 July 2016 in accordance with publisher's 'Terms and Conditions for Self-Archiving'. この論文は出版社版でありません。引用の際には出版社版をご確認ご利用ください。 This is not the published version. Please cite only the published version. |
URI: | http://hdl.handle.net/2433/202246 |
DOI(出版社版): | 10.1016/j.jstrokecerebrovasdis.2015.04.026 |
PubMed ID: | 26166418 |
出現コレクション: | 学術雑誌掲載論文等 |
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