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j.rmcr.2015.05.003.pdf | 1.3 MB | Adobe PDF | 見る/開く |
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dc.contributor.author | Tsuji, Takahiro | en |
dc.contributor.author | Kim, Young Hak | en |
dc.contributor.author | Ozasa, Hiroaki | en |
dc.contributor.author | Sakamori, Yuichi | en |
dc.contributor.author | Nagai, Hiroki | en |
dc.contributor.author | Ajimizu, Hitomi | en |
dc.contributor.author | Yagi, Yoshitaka | en |
dc.contributor.author | Furukawa, Atsuyuki | en |
dc.contributor.author | Haga, Hironori | en |
dc.contributor.author | Mishima, Michiaki | en |
dc.contributor.alternative | 金, 永学 | ja |
dc.contributor.alternative | 小笹, 裕見 | ja |
dc.contributor.alternative | 阪森, 優一 | ja |
dc.contributor.alternative | 羽賀, 博典 | ja |
dc.contributor.alternative | 三嶋, 理晃 | ja |
dc.date.accessioned | 2016-06-21T02:36:47Z | - |
dc.date.available | 2016-06-21T02:36:47Z | - |
dc.date.issued | 2015-05-01 | - |
dc.identifier.issn | 2213-0071 | - |
dc.identifier.uri | http://hdl.handle.net/2433/215118 | - |
dc.description.abstract | Introduction: Pulmonary spindle cell carcinoma (SpCC) is a rare subtype of non-small-cell lung cancer (NSCLC) and, in general, is chemoresistance. Case: A sixty-five year-old male patient with metastatic pulmonary SpCC was initially treated with cisplatin and docetaxel, but his disease progressed. Then, he received a combination chemotherapy with carboplatin and nab-PTX followed by maintenanced chemotherapy with nab-PTX. Fluorodeoxyglucose (FDG) positron-emission CT revealed a substantial decrease of FDG accumulation in the primary tumor, and the response continued for more than 7 months. Discussion: Preclinical models suggested that nab-PTX may reach the tumor microenvironment more efficiently than solvent-based paclitaxel (sb-PTX) and be preferentially taken up by cancer cells. Considering that there is no effective treatment for patients with pulmonary SpCC, nab-PTX may merit further investigation in patients with pulmonary SpCC. | en |
dc.format.mimetype | application/pdf | - |
dc.language.iso | eng | - |
dc.publisher | Elsevier Ltd. | en |
dc.rights | © 2015 The Authors. Published by Elsevier Ltd. This is an open access article under the CC BY-NC-ND license(http://creativecommons.org/licenses/by-nc-nd/4.0/). | en |
dc.subject | Pulmonary sarcomatoid carcinoma | en |
dc.subject | Spindle cell carcinoma | en |
dc.subject | Nab-PTX | en |
dc.title | Successful treatment with carboplatin and nanoparticle albumin-bound paclitaxel in a patient with pulmonary spindlecellcarcinoma | en |
dc.type | journal article | - |
dc.type.niitype | Journal Article | - |
dc.identifier.jtitle | Respiratory Medicine Case Reports | en |
dc.identifier.volume | 15 | - |
dc.identifier.spage | 48 | - |
dc.identifier.epage | 50 | - |
dc.relation.doi | 10.1016/j.rmcr.2015.05.003 | - |
dc.textversion | publisher | - |
dc.identifier.pmid | 26236601 | - |
dcterms.accessRights | open access | - |
出現コレクション: | 学術雑誌掲載論文等 |
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