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| ファイル | 記述 | サイズ | フォーマット | |
|---|---|---|---|---|
| nar_gkv662.pdf | 4.3 MB | Adobe PDF | 見る/開く |
| タイトル: | Linking two DNA duplexes with a rigid linker for DNA nanotechnology |
| 著者: | Tashiro, Ryu Iwamoto, Masahiro Morinaga, Hironobu Emura, Tomoko Hidaka, Kumi Endo, Masayuki  Sugiyama, Hiroshi   https://orcid.org/0000-0001-8923-5946 (unconfirmed) |
| 著者名の別形: | 森永, 浩伸 江村, 智子 日高, 久美 遠藤, 政幸 杉山, 弘 |
| 発行日: | 18-Aug-2015 |
| 出版者: | Oxford University Press (OUP) |
| 誌名: | Nucleic Acids Research |
| 巻: | 43 |
| 号: | 14 |
| 開始ページ: | 6692 |
| 終了ページ: | 6700 |
| 抄録: | DNA has recently emerged as a promising material for the construction of nanosized architectures. Chemically modified DNA has been suggested to be an important component of such architectural building blocks. We have designed and synthesized a novel H-shaped DNA oligonucleotide dimer that is cross-linked with a structurally rigid linker composed of phenylene and ethynylene groups. A rotatable DNA unit was constructed through the self-assembly of this H-shaped DNA component and two complementary DNA oligonucleotides. In addition to the rotatable unit, a locked DNA unit containing two H-shaped DNA components was also constructed. As an example of an extended locked structure, a hexagonal DNA origami dimer and oligomer were constructed by using H-shaped DNA as linkers. |
| 著作権等: | © The Author(s) 2015. Published by Oxford University Press on behalf of Nucleic Acids Research. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited. |
| URI: | http://hdl.handle.net/2433/215984 |
| DOI(出版社版): | 10.1093/nar/gkv662 |
| PubMed ID: | 26130712 |
| 出現コレクション: | 学術雑誌掲載論文等 |
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