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タイトル: | Effects of long-term exposure to 60 GHz millimeter-wavelength radiation on the genotoxicity and heat shock protein (HSP) expression of cells derived from human eye |
著者: | Koyama, Shin Narita, Eijiro Shimizu, Yoko Suzuki, Yukihisa Shiina, Takeo Taki, Masao Shinohara, Naoki Miyakoshi, Junji |
著者名の別形: | 小山, 眞 成田, 英二郎 藤原, 真毅 宮越, 順二 |
キーワード: | millimeter-waves cellular genotoxicity micronucleus formation comet assay heat shock protein long-term exposure human eye cells |
発行日: | 8-Aug-2016 |
出版者: | MDPI AG |
誌名: | International Journal of Environmental Research and Public Health |
巻: | 13 |
号: | 8 |
論文番号: | 802 |
抄録: | Human corneal epithelial (HCE-T) and human lens epithelial (SRA01/04) cells derived from the human eye were exposed to 60 gigahertz (GHz) millimeter-wavelength radiation for 24 h. There was no statistically significant increase in the micronucleus (MN) frequency in cells exposed to 60 GHz millimeter-wavelength radiation at 1 mW/cm2 compared with sham-exposed controls and incubator controls. The MN frequency of cells treated with bleomycin for 1 h provided positive controls. The comet assay, used to detect DNA strand breaks, and heat shock protein (Hsp) expression also showed no statistically significant effects of exposure. These results indicate that exposure to millimeter-wavelength radiation has no effect on genotoxicity in human eye cells. |
著作権等: | © 2016 by the authors; licensee MDPI, Basel, Switzerland. This is an open access article distributed under the Creative Commons Attribution License (CC BY 4.0). |
URI: | http://hdl.handle.net/2433/216504 |
DOI(出版社版): | 10.3390/ijerph13080802 |
PubMed ID: | 27509516 |
出現コレクション: | 学術雑誌掲載論文等 |
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