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Title: Effects of long-term exposure to 60 GHz millimeter-wavelength radiation on the genotoxicity and heat shock protein (HSP) expression of cells derived from human eye
Authors: Koyama, Shin  kyouindb  KAKEN_id
Narita, Eijiro
Shimizu, Yoko
Suzuki, Yukihisa
Shiina, Takeo
Taki, Masao
Shinohara, Naoki  kyouindb  KAKEN_id
Miyakoshi, Junji  kyouindb  KAKEN_id
Author's alias: 小山, 眞
成田, 英二郎
藤原, 真毅
宮越, 順二
Keywords: millimeter-waves
cellular genotoxicity
micronucleus formation
comet assay
heat shock protein
long-term exposure
human eye cells
Issue Date: 8-Aug-2016
Publisher: MDPI AG
Journal title: International Journal of Environmental Research and Public Health
Volume: 13
Issue: 8
Thesis number: 802
Abstract: Human corneal epithelial (HCE-T) and human lens epithelial (SRA01/04) cells derived from the human eye were exposed to 60 gigahertz (GHz) millimeter-wavelength radiation for 24 h. There was no statistically significant increase in the micronucleus (MN) frequency in cells exposed to 60 GHz millimeter-wavelength radiation at 1 mW/cm2 compared with sham-exposed controls and incubator controls. The MN frequency of cells treated with bleomycin for 1 h provided positive controls. The comet assay, used to detect DNA strand breaks, and heat shock protein (Hsp) expression also showed no statistically significant effects of exposure. These results indicate that exposure to millimeter-wavelength radiation has no effect on genotoxicity in human eye cells.
Rights: © 2016 by the authors; licensee MDPI, Basel, Switzerland.
This is an open access article distributed under the Creative Commons Attribution License (CC BY 4.0).
DOI(Published Version): 10.3390/ijerph13080802
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