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タイトル: | 化学療法施行中に重症心筋梗塞を発症した後腹膜原発胚細胞腫の1例 |
その他のタイトル: | Severe Acute Myocardial Infarction during Induction Chemotherapy for Retroperitoneal Germ Cell Tumor : A Case Report |
著者: | 目, 翔太郎 河合, 弘二 辻本, 一平 黒部, 匡広 市岡, 大士 神鳥, 周也 小島, 崇宏 末富, 崇弘 常樂, 晃 宮崎, 淳 星, 智也 西山, 博之 |
著者名の別形: | Sakka, Shotaro Kawai, Koji Tsujimoto, Ippei Kurobe, Masahiro Ichioka, Daishi Kantori, Shuya Kojima, Takahiro Suetomi, Takahiro Jouraku, Akira Miyazaki, Jun Hoshi, Tomoya Nishiyama, Hiroyuki |
キーワード: | Acute myocardial infarction Chemotherapy Testicular cancer |
発行日: | 30-Sep-2016 |
出版者: | 泌尿器科紀要刊行会 |
誌名: | 泌尿器科紀要 |
巻: | 62 |
号: | 9 |
開始ページ: | 483 |
終了ページ: | 487 |
抄録: | A 37-year-old man presented at our hospital. Pathological examination of a right orchiectomy specimen, radiographic examination, and tumor marker profile resulted in a diagnosis of retroperitoneal nonseminomatous germ cell tumor (intermediate risk according to IGCC classification). Laboratory testing revealed mild elevation of low density lipoprotein cholesterol. Induction chemotherapy with bleomycin, etoposide and cisplatin (BEP) was started, but he complained of chest pain on day 10 of the second cycle of BEP. We immediately started cardiac monitoring. One hour later, he suffered cardiac arrest due to ventricular fibrillation. Fortunately, sinus rhythm was restored after defibrillation. A diagnosis of acute myocardial infarction (AMI) with total occlusion at the mid-portion of the left anterior descending coronary artery was established by coronary angiography. After percutaneous transluminal coronary angioplasty was successfully performed, he recovered uneventfully. The induction chemotherapy was re-started 19 days after AMI. To avoid endothelial damage by bleomycin, we elected to treat with etoposide, ifosfamide, and cisplatin (VIP). After two further courses of VIP, the patient underwent resection of retoperitoneal tumor and achieved complete remission. The patient has remained disease-free during 3 years follow up without recurrence of AMI. |
著作権等: | 許諾条件により本文は2017/10/01に公開 |
DOI: | 10.14989/ActaUrolJap_62_9_483 |
URI: | http://hdl.handle.net/2433/217049 |
PubMed ID: | 27760974 |
出現コレクション: | Vol.62 No.9 |
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