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タイトル: The mechanics clarifying counterclockwise rotation in most IVF eggs in mice
著者: Ishimoto, Kenta  kyouindb  KAKEN_id
Ikawa, Masahito
Okabe, Masaru
著者名の別形: 石本, 健太
発行日: 3-Mar-2017
出版者: Springer Nature
誌名: Scientific Reports
巻: 7
論文番号: 43456
抄録: In mammalian fertilization, a small spermatozoon interacts with an egg that is a few thousand times larger in volume. In spite of the big difference in size and mass, when spermatozoa are bound to eggs, they begin rotating the eggs in in vitro observation. This was dubbed the ‘fertilization dance’. Interestingly, some papers reported that the rotation was counterclockwise, although the reason for this skewed rotation was not clarified. We focused on a chirality of helical beating of spermatozoa and found that eggs rotate counterclockwise in simulations under a certain geometrical condition where the eggs were situated. This theory of egg rotation was validated by demonstrating egg rotation in a clockwise direction by floating eggs to the upper surface of the IVF medium. The enigma of skewed rotation of IVF eggs was clarified.
著作権等: This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/
URI: http://hdl.handle.net/2433/224808
DOI(出版社版): 10.1038/srep43456
出現コレクション:学術雑誌掲載論文等

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