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タイトル: | 尿道ブジー後にBCG膀胱内注入療法を施行し, 発熱, 肝機能障害, 間質性肺炎を認めた1例 |
その他のタイトル: | Fever, Hepatic Dysfunction and Interstitial Pneumonia Caused by Intravesical Bacillus Calmette-Guerin (BCG) Instillation after Urethral Bougie : A Case Report |
著者: | 新田, 聡 目, 翔太郎 遠藤, 剛 小峯, 学 堤, 雅一 西山, 博之 |
著者名の別形: | Nitta, Satoshi Sakka, Shotaro Endo, Tsuyoshi Komine, Manabu Tsutsumi, Masakazu Nishiyama, Hiroyuki |
キーワード: | BCG Hypersensitivity reaction |
発行日: | 31-Oct-2017 |
出版者: | 泌尿器科紀要刊行会 |
誌名: | 泌尿器科紀要 |
巻: | 63 |
号: | 10 |
開始ページ: | 427 |
終了ページ: | 430 |
抄録: | A 60-year-old man had a past history of urothelial carcinoma of the left renal pelvis treated with laparoscopic left total nephroureterectomy in October 2004. He underwent transurethral resection of the bladder tumor (TUR-Bt) twice for recurrence of urothelial carcinoma in the bladder in April 2014 and February 2015, and subsequently received intravesical Bacillus Calmette-Guerin (BCG) instillation at weekly intervalsfor prevention of recurrence. In November 2016, a year and a half after BCG induction, he received BCG therapy after urethral bougie to dilate the urethral stricture. After BCG therapy, he exhibited a continuously high fever. Immediate antituberculosis drug therapy in consideration of BCG sepsis failed to improve the symptoms, and all cultures from urine and blood were negative for mycobacterium tuberculosis. Serum liver enzyme was markedly elevated and chest CT showed diffuse interstitial shadows in both lower lungs. Thus, we considered that these symptoms were caused by a hypersensitivity reaction to BCG and started pulse steroid therapy. After pulse steroid therapy, body temperature, and hepatic function became normal and interstitial pneumonia subsided. |
著作権等: | 許諾条件により本文は2018/11/01に公開 |
DOI: | 10.14989/ActaUrolJap_63_10_427 |
URI: | http://hdl.handle.net/2433/227800 |
PubMed ID: | 29103257 |
出現コレクション: | Vol.63 No.10 |
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