このアイテムのアクセス数: 278
このアイテムのファイル:
| ファイル | 記述 | サイズ | フォーマット | |
|---|---|---|---|---|
| BMBRep.2017.50.4.040.pdf | 1.71 MB | Adobe PDF | 見る/開く |
| タイトル: | Translational control of mRNAs by 3'-Untranslated region binding proteins |
| 著者: | Yamashita, Akio Takeuchi, Osamu    https://orcid.org/0000-0002-1260-6232 (unconfirmed) |
| 著者名の別形: | 竹内, 理 |
| キーワード: | RNA binding protein Translation ranslation initiation 3`-UTR |
| 発行日: | 30-Apr-2017 |
| 出版者: | Korean Society for Biochemistry and Molecular Biology - BMB Reports |
| 誌名: | BMB Reports |
| 巻: | 50 |
| 号: | 4 |
| 開始ページ: | 194 |
| 終了ページ: | 200 |
| 抄録: | Eukaryotic gene expression is precisely regulated at all points between transcription and translation. In this review, we focus on translational control mediated by the 3`-untranslated regions (UTRs) of mRNAs. mRNA 3`-UTRs contain cis-acting elements that function in the regulation of protein translation or mRNA decay. Each RNA binding protein that binds to these cis-acting elements regulates mRNA translation via various mechanisms targeting the mRNA cap structure, the eukaryotic initiation factor 4E (eIF4E)-eIF4G complex, ribosomes, and the poly (A) tail. We also discuss translation-mediated regulation of mRNA fate. |
| 著作権等: | Copyright © 2017 by the The Korean Society for Biochemistry and Molecular Biology This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
| URI: | http://hdl.handle.net/2433/227867 |
| DOI(出版社版): | 10.5483/BMBRep.2017.50.4.040 |
| PubMed ID: | 28287067 |
| 出現コレクション: | 学術雑誌掲載論文等 |
このリポジトリに保管されているアイテムはすべて著作権により保護されています。