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| ファイル | 記述 | サイズ | フォーマット | |
|---|---|---|---|---|
| BMBRep.2017.50.4.040.pdf | 1.71 MB | Adobe PDF | 見る/開く |
| タイトル: | Translational control of mRNAs by 3'-Untranslated region binding proteins |
| 著者: | Yamashita, Akio Takeuchi, Osamu    https://orcid.org/0000-0002-1260-6232 (unconfirmed) |
| 著者名の別形: | 竹内, 理 |
| キーワード: | RNA binding protein Translation ranslation initiation 3`-UTR |
| 発行日: | 30-Apr-2017 |
| 出版者: | Korean Society for Biochemistry and Molecular Biology - BMB Reports |
| 誌名: | BMB Reports |
| 巻: | 50 |
| 号: | 4 |
| 開始ページ: | 194 |
| 終了ページ: | 200 |
| 抄録: | Eukaryotic gene expression is precisely regulated at all points between transcription and translation. In this review, we focus on translational control mediated by the 3`-untranslated regions (UTRs) of mRNAs. mRNA 3`-UTRs contain cis-acting elements that function in the regulation of protein translation or mRNA decay. Each RNA binding protein that binds to these cis-acting elements regulates mRNA translation via various mechanisms targeting the mRNA cap structure, the eukaryotic initiation factor 4E (eIF4E)-eIF4G complex, ribosomes, and the poly (A) tail. We also discuss translation-mediated regulation of mRNA fate. |
| 著作権等: | Copyright © 2017 by the The Korean Society for Biochemistry and Molecular Biology This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
| URI: | http://hdl.handle.net/2433/227867 |
| DOI(出版社版): | 10.5483/BMBRep.2017.50.4.040 |
| PubMed ID: | 28287067 |
| 出現コレクション: | 学術雑誌掲載論文等 |
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