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Title: Acute Effects of Ambient PM2.5 on All-Cause and Cause-Specific Emergency Ambulance Dispatches in Japan
Authors: Phung, Vera
Ueda, Kayo  kyouindb  KAKEN_id  orcid https://orcid.org/0000-0002-2104-1384 (unconfirmed)
Kasaoka, Shunji
Seposo, Xerxes
Tasmin, Saira
Yonemochi, Shinichi
Phosri, Arthit
Honda, Akiko  kyouindb  KAKEN_id  orcid https://orcid.org/0000-0002-7358-4372 (unconfirmed)
Takano, Hirohisa  kyouindb  KAKEN_id
Michikawa, Takehiro
Nitta, Hiroshi
Author's alias: 上田, 佳代
本田, 晶子
高野, 裕久
Keywords: air pollution
ambient PM₂.₅
emergency ambulance dispatches
short-term exposure
Issue Date: 9-Feb-2018
Publisher: MDPI AG
Journal title: International Journal of Environmental Research and Public Health
Volume: 15
Issue: 2
Thesis number: 307
Abstract: Short-term health effects of ambient PM₂.₅ have been established with numerous studies, but evidence in Asian countries is limited. This study aimed to investigate the short-term effects of PM₂.₅ on acute health outcomes, particularly all-cause, cardiovascular, respiratory, cerebrovascular and neuropsychological outcomes. We utilized daily emergency ambulance dispatches (EAD) data from eight Japanese cities (2007–2011). Statistical analyses included two stages: (1) City-level generalized linear model with Poisson distribution; (2) Random-effects meta-analysis in pooling city-specific effect estimates. Lag patterns were explored using (1) unconstrained-distributed lags (lag 0 to lag 7) and (2) average lags (lag: 0–1, 0–3, 0–5, 0–7). In all-cause EAD, significant increases were observed in both shorter lag (lag 0: 1.24% (95% CI: 0.92, 1.56)) and average lag 0–1 (0.64% (95% CI: 0.23, 1.06)). Increases of 1.88% and 1.48% in respiratory and neuropsychological EAD outcomes, respectively, were observed at lag 0 per 10 µg/m3 increase in PM₂.₅. While respiratory outcomes demonstrated significant average effects, no significant effect was observed for cardiovascular outcomes. Meanwhile, an inverse association was observed in cerebrovascular outcomes. In this study, we observed that effects of PM₂.₅ on all-cause, respiratory and neuropsychological EAD were acute, with average effects not exceeding 3 days prior to EAD onset.
Rights: © 2018 by the authors. Licensee MDPI, Basel, Switzerland. This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).
URI: http://hdl.handle.net/2433/233953
DOI(Published Version): 10.3390/ijerph15020307
PubMed ID: 29425190
Appears in Collections:Journal Articles

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