このアイテムのアクセス数: 261
このアイテムのファイル:
ファイル | 記述 | サイズ | フォーマット | |
---|---|---|---|---|
j.pacs.2018.06.002.pdf | 1.6 MB | Adobe PDF | 見る/開く |
タイトル: | Vascular branching point counts using photoacoustic imaging in the superficial layer of the breast: A potential biomarker for breast cancer |
著者: | Yamaga, Iku Kawaguchi-Sakita, Nobuko Asao, Yasufumi Matsumoto, Yoshiaki ![]() ![]() Yoshikawa, Aya Fukui, Toshifumi Takada, Masahiro ![]() ![]() ![]() Kataoka, Masako ![]() ![]() ![]() Kawashima, Masahiro ![]() ![]() ![]() Fakhrejahani, Elham Kanao, Shotaro Nakayama, Yoshie Tokiwa, Mariko Torii, Masae Yagi, Takayuki Sakurai, Takaki Haga, Hironori ![]() ![]() Togashi, Kaori Shiina, Tsuyoshi ![]() Toi, Masakazu ![]() ![]() |
著者名の別形: | 山賀, 郁 川口, 展子 松本, 純明 髙田, 正泰 片岡, 正子 川島, 雅央 金尾, 昌太郎 中山, 美恵 常盤, 麻里子 鳥井, 雅恵 桜井, 孝規 羽賀, 博典 富樫, かおり 椎名, 毅 戸井, 雅和 |
キーワード: | biomarker breast cancer photoacoustic imaging vasculature vessel branching points |
発行日: | Sep-2018 |
出版者: | Elsevier BV |
誌名: | Photoacoustics |
巻: | 11 |
開始ページ: | 6 |
終了ページ: | 13 |
抄録: | This study aimed to identify the characteristics of the vascular network in the superficial subcutaneous layer of the breast and to analyze differences between breasts with cancer and contralateral unaffected breasts using vessel branching points (VBPs) detected by three-dimensional photoacoustic imaging with a hemispherical detector array. In 22 patients with unilateral breast cancer, the average VBP counts to a depth of 7 mm below the skin surface were significantly greater in breasts with cancer than in the contralateral unaffected breasts (p < 0.01). The ratio of the VBP count in the breasts with cancer to that in the contralateral breasts was significantly increased in patients with a high histologic grade (p = 0.03), those with estrogen receptor-negative disease (p < 0.01), and those with highly proliferative disease (p < 0.01). These preliminary findings indicate that a higher number of VBPs in the superficial subcutaneous layer of the breast might be a biomarker for primary breast cancer. |
著作権等: | © 2018 The Authors. Published by Elsevier GmbH. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/BY-NC-ND/4.0/). |
URI: | http://hdl.handle.net/2433/234594 |
DOI(出版社版): | 10.1016/j.pacs.2018.06.002 |
PubMed ID: | 30003041 |
出現コレクション: | 学術雑誌掲載論文等 |

このリポジトリに保管されているアイテムはすべて著作権により保護されています。