このアイテムのアクセス数: 221
このアイテムのファイル:
| ファイル | 記述 | サイズ | フォーマット | |
|---|---|---|---|---|
| s41598-018-31579-z.pdf | 1.73 MB | Adobe PDF | 見る/開く |
| タイトル: | Three-dimensional motion analysis for comprehensive understanding of gait characteristics after sciatic nerve lesion in rodents |
| 著者: | Tajino, Junichi Ito, Akira    https://orcid.org/0000-0002-9645-9777 (unconfirmed)Tanima, Momoko https://orcid.org/0000-0003-3972-8800 (unconfirmed)Yamaguchi, Shoki Iijima, Hirotaka Nakahata, Akihiro Kiyan, Wataru Aoyama, Tomoki https://orcid.org/0009-0002-5172-5477 (unconfirmed)Kuroki, Hiroshi |
| 著者名の別形: | 太治野, 純一 伊藤, 明良 谷間, 桃子 山口, 将希 飯島, 弘貴 中畑, 晶博 喜屋武, 弥 青山, 朋樹 黒木, 裕士 |
| 発行日: | 11-Sep-2018 |
| 出版者: | Springer Nature America, Inc |
| 誌名: | Scientific reports |
| 巻: | 8 |
| 号: | 1 |
| 論文番号: | 13585 |
| 抄録: | Rodent models of sciatic nerve lesion are regularly used to assess functional deficits in nerves. Impaired locomotor functions induced by sciatic nerve lesion are currently evaluated with scoring systems despite their limitations. To overcome these shortcomings, which includes low sensitivity, little significance, and the representation of only marginal components of motion profiles, some additional metrics have been introduced. However, a quantitative determination of motion deficits is yet to be established. We used a three-dimensional motion analysis to investigate gait deficits after sciatic nerve lesion in rats. This enabled us to depict the distorted gait motion using both traditional parameters and novel readouts that are specific for the three-dimensional analysis. Our results suggest that three-dimensional motion analysis facilitates a comprehensive understanding of the gait impairment specifically, but not limited to, a sciatic lesion rat model. A broad application of these methods will improve understanding and standardized motor assessment. |
| 著作権等: | © The Author(s) 2018. This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/. |
| URI: | http://hdl.handle.net/2433/234697 |
| DOI(出版社版): | 10.1038/s41598-018-31579-z |
| PubMed ID: | 30206259 |
| 出現コレクション: | 学術雑誌掲載論文等 |
このリポジトリに保管されているアイテムはすべて著作権により保護されています。