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Title: Relationship between Ocular Deviation and Visual Function in Retinitis Pigmentosa
Authors: Miyata, Manabu  kyouindb  KAKEN_id  orcid https://orcid.org/0000-0002-7574-1749 (unconfirmed)
Oishi, Akio
Ogino, Ken
Oishi, Maho
Hasegawa, Tomoko
Nagasaku, Yuko
Ikeda, Hanako Ohashi
Ohtsuki, Hiroshi
Tsujikawa, Akitaka  kyouindb  KAKEN_id
Author's alias: 宮田, 学
大石, 明生
荻野, 顕
大石, 真秀
長谷川, 智子
池田, 華子
辻川, 明孝
Issue Date: 5-Oct-2018
Publisher: Springer Nature America, Inc
Journal title: Scientific Reports
Volume: 8
Issue: 1
Thesis number: 14880
Abstract: In retinitis pigmentosa (RP), peripheral visual-field loss starts in early stages, whereas central vision loss occurs in advanced stages. Sensory strabismus gradually occurs in RP. We investigated the relationship between ocular deviation and visual function and explored for sensory strabismus risk factors in 119 consecutive patients with RP at various stages. We assessed ocular deviation at far and near distances, that is the central visual field, using the mean deviation (MD) value and visual acuity (VA), and the residual binocular field area, using Goldmann perimetry (GP), in 33 patients. The horizontal ocular deviation at near distance was >10° in 30% patients and correlated with residual visual function. Although there was no effective cut-off value for central visual function, a cut-off residual GP area of 40 cm2 distinguished patients with a larger from those with a smaller horizontal ocular deviation at far distance (P = 0.04). Our findings suggest that visual function is negatively associated with ocular deviation in patients with RP and that the sensory strabismus risk is relatively high for patients with a binocular visual field <40 cm2. Thus, screening for ocular alignment may be necessary for patients with RP-associated severe vision loss as part of their comprehensive care.
Rights: This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
URI: http://hdl.handle.net/2433/234699
DOI(Published Version): 10.1038/s41598-018-33211-6
PubMed ID: 30291281
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