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タイトル: | Global, regional, and national burden of migraine and tension-type headache, 1990-2016: a systematic analysis for the Global Burden of Disease Study 2016 |
著者: | Stovner, Lars Jacob Nichols, Emma Steiner, Timothy J Abd-Allah, Foad Abdelalim, Ahmed Al-Raddadi, Rajaa M Ansha, Mustafa Geleto Barac, Aleksandra Bensenor, Isabela M Doan, Linh Phuong Edessa, Dumessa Endres, Matthias Foreman, Kyle J Gankpe, Fortune Gbetoho Gopalkrishna, Gururaj Goulart, Alessandra C Gupta, Rahul Hankey, Graeme J Hay, Simon I Hegazy, Mohamed I Hilawe, Esayas Haregot Kasaeian, Amir Kassa, Dessalegn H Khalil, Ibrahim Khang, Young-Ho Khubchandan, Jagdish Kim, Yun Jin Kokubo, Yoshihiro Mohammed, Mohammed A Moradi-Lakeh, Maziar Nguyen, Huong Lan Thi Nirayo, Yirga Legesse Qorbani, Mostafa Ranta, Anna Roba, Kedir T Safiri, Saeid Santos, Itamar S Satpathy, Maheswar Sawhney, Monika Shiferaw, Mekonnen Sisay Shiue, Ivy Smith, Mari Szoeke, Cassandra E I Truong, Nu Thi Venketasubramanian, Narayanaswamy weldegwergs, Kidu gidey Westerman, Ronny Wijeratne, Tissa Tran, Bach Xuan Yonemoto, Naohiro Feigin, Valery L Vos, Theo Murray, Christopher J L |
著者名の別形: | 米本, 直裕 |
発行日: | Nov-2018 |
出版者: | Elsevier BV |
誌名: | The Lancet Neurology |
巻: | 17 |
号: | 11 |
開始ページ: | 954 |
終了ページ: | 976 |
抄録: | [Background] Through the Global Burden of Diseases, Injuries, and Risk Factors (GBD) studies, headache has emerged as a major global public health concern. We aimed to use data from the GBD 2016 study to provide new estimates for prevalence and years of life lived with disability (YLDs) for migraine and tension-type headache and to present the methods and results in an accessible way for clinicians and researchers of headache disorders. [Methods] Data were derived from population-based cross-sectional surveys on migraine and tension-type headache. Prevalence for each sex and 5-year age group interval (ie, age 5 years to ≥95 years) at different time points from 1990 and 2016 in all countries and GBD regions were estimated using a Bayesian meta-regression model. Disease burden measured in YLDs was calculated from prevalence and average time spent with headache multiplied by disability weights (a measure of the relative severity of the disabling consequence of a disease). The burden stemming from medication overuse headache, which was included in earlier iterations of GBD as a separate cause, was subsumed as a sequela of either migraine or tension-type headache. Because no deaths were assigned to headaches as the underlying cause, YLDs equate to disability-adjusted life-years (DALYs). We also analysed results on the basis of the Socio-demographic Index (SDI), a compound measure of income per capita, education, and fertility. [Findings] Almost three billion individuals were estimated to have a migraine or tension-type headache in 2016: 1·89 billion (95% uncertainty interval [UI] 1·71–2·10) with tension-type headache and 1·04 billion (95% UI 1·00–1·09) with migraine. However, because migraine had a much higher disability weight than tension-type headache, migraine caused 45·1 million (95% UI 29·0–62·8) and tension-type headache only 7·2 million (95% UI 4·6–10·5) YLDs globally in 2016. The headaches were most burdensome in women between ages 15 and 49 years, with migraine causing 20·3 million (95% UI 12·9–28·5) and tension-type headache 2·9 million (95% UI 1·8–4·2) YLDs in 2016, which was 11·2% of all YLDs in this age group and sex. Age-standardised DALYs for each headache type showed a small increase as SDI increased. [Interpretation] Although current estimates are based on limited data, our study shows that headache disorders, and migraine in particular, are important causes of disability worldwide, and deserve greater attention in health policy debates and research resource allocation. Future iterations of this study, based on sources from additional countries and with less methodological heterogeneity, should help to provide stronger evidence of the need for action. [Funding] Bill & Melinda Gates Foundation. |
著作権等: | © 2018 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY 4.0 license. |
URI: | http://hdl.handle.net/2433/235005 |
DOI(出版社版): | 10.1016/S1474-4422(18)30322-3 |
PubMed ID: | 30353868 |
出現コレクション: | 学術雑誌掲載論文等 |
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