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| ファイル | 記述 | サイズ | フォーマット | |
|---|---|---|---|---|
| acs.orglett.6b00943.pdf | 648.27 kB | Adobe PDF | 見る/開く |
| タイトル: | Synthesis of CPZEN-45: Construction of the 1,4-Diazepin-2-one Core by the Cu-Catalyzed Intramolecular Amidation of a Vinyl Iodide |
| 著者: | Nakamura, Hugh Yoshida, Takuma Tsukano, Chihiro    https://orcid.org/0000-0002-9361-0857 (unconfirmed)Takemoto, Yoshiji https://orcid.org/0000-0003-1375-3821 (unconfirmed) |
| 著者名の別形: | 中村, 斐有 吉田, 拓馬 塚野, 千尋 竹本, 佳司 |
| 発行日: | 6-May-2016 |
| 出版者: | American Chemical Society |
| 誌名: | Organic Letters |
| 巻: | 18 |
| 号: | 9 |
| 開始ページ: | 2300 |
| 終了ページ: | 2303 |
| 抄録: | CPZEN-45 was developed as an antibiotic against Mycobacterium tuberculosis by the chemical modification of caprazamycins. CPZEN-45 has been synthesized in this study by the Cu-catalyzed intramolecular amidation of a complex vinyl iodide precursor bearing uridine and sugar moieties with a secondary amide, allowing for the construction of its 1, 4-diazepin-2-one core. |
| 著作権等: | This document is the Accepted Manuscript version of a Published Work that appeared in final form in Organic Letters, copyright © American Chemical Society after peer review and technical editing by the publisher. To access the final edited and published work see https://doi.org/10.1021/acs.orglett.6b00943. この論文は出版社版でありません。引用の際には出版社版をご確認ご利用ください。 This is not the published version. Please cite only the published version. |
| URI: | http://hdl.handle.net/2433/235940 |
| DOI(出版社版): | 10.1021/acs.orglett.6b00943 |
| PubMed ID: | 27088563 |
| 出現コレクション: | 学術雑誌掲載論文等 |
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