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タイトル: Interaction of psoriasis and bullous diseases
著者: Dainichi, Teruki
Kabashima, Kenji  kyouindb  KAKEN_id  orcid https://orcid.org/0000-0002-0773-0554 (unconfirmed)
著者名の別形: 大日, 輝記
椛島, 健治
キーワード: autoimmunity
Th2
Th17
psoriasis
pemphigoid
laminin
MMP
senescence
発行日: 1-Jan-2018
出版者: Frontiers Media SA
誌名: Frontiers in Medicine
巻: 5
論文番号: 222
抄録: Patients with psoriasis are frequently complicated with autoimmune bullous diseases, especially, pemphigoid diseases. It has been known that one-third cases of anti-laminin gamma1 pemphigoid, formerly anti-p200 pemphigoid, are associated with psoriasis whereas bullous pemphigoid is the most frequently associated bullous disease in psoriasis cases regardless of the lack of detectable levels of the accompanying anti-laminin gamma1 autoantibodies. Despite several suggestions, however, the definitive reason of the striking association of psoriasis and these autoimmune bullous diseases remains elusive. In this review, we look over the epidemiological evidence of the association of psoriasis and autoimmune bullous diseases and the information of genetic susceptibilities of each disease, and discuss the possible mechanisms of their complication with reference to the recent understandings of each pathogenesis.
著作権等: © 2018 Dainichi and Kabashima. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
URI: http://hdl.handle.net/2433/237331
DOI(出版社版): 10.3389/fmed.2018.00222
PubMed ID: 30135860
出現コレクション:学術雑誌掲載論文等

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