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タイトル: | Risk of myocardial infarction in patients with psoriasis: A cross-sectional patient-population study in a Japanese hospital |
著者: | Shiba, Masayuki Kato, Takao https://orcid.org/0000-0001-8213-7999 (unconfirmed) Izumi, Toshiaki Miyamoto, Shoichi Nakane, Eisaku Haruna, Tetsuya Inoko, Moriaki |
著者名の別形: | 加藤, 貴雄 |
キーワード: | Psoriasis Myocardial infarction Japan |
発行日: | Apr-2019 |
出版者: | Elsevier Ltd. |
誌名: | Journal of Cardiology |
巻: | 73 |
号: | 4 |
開始ページ: | 276 |
終了ページ: | 279 |
抄録: | [Background]Some epidemiological studies have demonstrated the association between psoriasis vulgaris and coronary artery disease (CAD). However, there is a lack of specific data regarding the association between psoriasis vulgaris and myocardial infarction (MI), the more severe and critical presentation of CAD, in the Japanese population. [Methods and results]We retrospectively analyzed 113, 065 patients of all ages at our hospital from January 1, 2011 to January 1, 2013. We extracted the data of patients with psoriasis vulgaris, diabetes mellitus, dyslipidemia, or MI (acute, sub-acute, or old), including sex and age from the electronic medical record database. The prevalence of MI in patients with hypertension, dyslipidemia, diabetes mellitus, and psoriasis vulgaris were 4.8% (794/16, 476), 5.0% (459/9236), 4.6% (531/11, 555), and 2.7% (32/1197), respectively. Multivariate analysis showed that psoriasis vulgaris was significantly associated with MI [adjusted odds ratio (OR): 1.87; 95% confidence interval (CI): 1.26–2.68; p = 0.0022]. In a subgroup analysis of 24, 069 patients who had one or more comorbidities including diabetes mellitus, dyslipidemia, and hypertension, psoriasis vulgaris was still independently associated with MI after adjusting for sex and age (adjusted OR, 1.49; 95% CI: 1.02–2.18; p = 0.0358) in adults. [Conclusion]Psoriasis vulgaris was significantly associated with MI in a Japanese hospital-based population. |
著作権等: | © 2018. This manuscript version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/ The full-text file will be made open to the public on 1 April 2020 in accordance with publisher's 'Terms and Conditions for Self-Archiving'. This is not the published version. Please cite only the published version. この論文は出版社版でありません。引用の際には出版社版をご確認ご利用ください。 |
URI: | http://hdl.handle.net/2433/241616 |
DOI(出版社版): | 10.1016/j.jjcc.2018.10.008 |
PubMed ID: | 30583988 |
出現コレクション: | 学術雑誌掲載論文等 |
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