Access count of this item: 11

Files in This Item:
File Description SizeFormat 
j.etap.2017.04.019.pdf622.58 kBAdobe PDFView/Open
Title: Synergic effects of 9,10-phenanthrenequinone and cadmium on pro-inflammatory responses in airway epithelial cells
Authors: Honda, Akiko
Chowdhury, Pratiti Home
Ito, Sho
Okano, Hitoshi
Onishi, Toshinori
Kawaryu, Yusuke
Ueda, Kayo
Takano, Hirohisa
Author's alias: 本田, 晶子
上田, 佳代
高野, 裕久
Keywords: Cadmium
9, 10-Phenanthrenequinone
Synergic effects
Airway inflammation
PM2.5
Issue Date: Jun-2017
Publisher: Elsevier BV
Journal title: Environmental Toxicology and Pharmacology
Volume: 52
Start page: 276
End page: 279
Abstract: We investigated the synergic effects of components of particulate matter with aerodynamic diameters ≤2.5 μm (PM2.5) on airway inflammation. Co-exposure to cadmium (Cd) and 9, 10-phenanthrenequinone (9, 10-PQ) additively/synergistically increased pro-inflammatory responses in airway epithelial cells, whereas co-exposure to Cd and phenanthrene resulted in no acceleration. These results suggest that the combination of metal and a quinone derivative can contribute to the exacerbation of respiratory diseases by PM2.5.
Rights: © 2017. This manuscript version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/
The full-text file will be made open to the public on 1 June 2018 in accordance with publisher's 'Terms and Conditions for Self-Archiving'.
This is not the published version. Please cite only the published version. この論文は出版社版でありません。引用の際には出版社版をご確認ご利用ください。
URI: http://hdl.handle.net/2433/243827
DOI(Published Version): 10.1016/j.etap.2017.04.019
Appears in Collections:Journal Articles

Show full item record

Export to RefWorks


Export Format: 


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.