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j.etap.2017.04.019.pdf | 622.58 kB | Adobe PDF | 見る/開く |
タイトル: | Synergic effects of 9,10-phenanthrenequinone and cadmium on pro-inflammatory responses in airway epithelial cells |
著者: | Honda, Akiko https://orcid.org/0000-0002-7358-4372 (unconfirmed) Chowdhury, Pratiti Home Ito, Sho Okano, Hitoshi Onishi, Toshinori Kawaryu, Yusuke Ueda, Kayo https://orcid.org/0000-0002-2104-1384 (unconfirmed) Takano, Hirohisa https://orcid.org/0000-0002-3748-6206 (unconfirmed) |
著者名の別形: | 本田, 晶子 上田, 佳代 高野, 裕久 |
キーワード: | Cadmium 9, 10-Phenanthrenequinone Synergic effects Airway inflammation PM2.5 |
発行日: | Jun-2017 |
出版者: | Elsevier BV |
誌名: | Environmental Toxicology and Pharmacology |
巻: | 52 |
開始ページ: | 276 |
終了ページ: | 279 |
抄録: | We investigated the synergic effects of components of particulate matter with aerodynamic diameters ≤2.5 μm (PM2.5) on airway inflammation. Co-exposure to cadmium (Cd) and 9, 10-phenanthrenequinone (9, 10-PQ) additively/synergistically increased pro-inflammatory responses in airway epithelial cells, whereas co-exposure to Cd and phenanthrene resulted in no acceleration. These results suggest that the combination of metal and a quinone derivative can contribute to the exacerbation of respiratory diseases by PM2.5. |
著作権等: | © 2017. This manuscript version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/ The full-text file will be made open to the public on 1 June 2018 in accordance with publisher's 'Terms and Conditions for Self-Archiving'. This is not the published version. Please cite only the published version. この論文は出版社版でありません。引用の際には出版社版をご確認ご利用ください。 |
URI: | http://hdl.handle.net/2433/243827 |
DOI(出版社版): | 10.1016/j.etap.2017.04.019 |
PubMed ID: | 28477472 |
出現コレクション: | 学術雑誌掲載論文等 |
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