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タイトル: | Particle and rigidized red blood cell concentration distributions in microchannel flows |
著者: | Tatsumi, Kazuya Noguchi, Shinnosuke Tatsumi, Akira Kuriyama, Reiko https://orcid.org/0000-0003-3619-7370 (unconfirmed) Nakabe, Kazuyoshi |
著者名の別形: | 巽, 和也 野口, 真之介 辰巳, 朗 栗山, 怜子 中部, 主敬 |
キーワード: | Condensed Matter Physics |
発行日: | Aug-2019 |
出版者: | AIP Publishing |
誌名: | Physics of Fluids |
巻: | 31 |
号: | 8 |
論文番号: | 082006 |
抄録: | The motion and concentration distribution of particles and cells in flow are important factors which affect the fluid properties, flow structure, and mass transfer of biological and chemical species in blood vessels and channels. In this study, number density distributions of particles and rigidized red blood cells (RBCs) in a microchannel whose size is comparable to the sizes of the particle and RBCs are measured. Measurements were conducted at several streamwise locations for suspensions of particles and RBCs with hematocrits of the order of 10% and particle sizes of 5 and 8 µm. Analysis of the migration and resulting concentration distribution of the particles and RBCs was conducted using a model that considers the particle–particle collision and fluid dynamic force. As the size of the microchannel is small, the wall effect on the collision and migration of the particles and RBCs was significant. The wall reduced the overlapping area of the particles in collision and their displacement after collision (mobility), which varied the number, location, and magnitude of the maximum peaks observed in the number density distribution. Furthermore, the rotational motion of the rigidized RBCs in the channel flow reduced the effective lengths of the overlapping area and displacement, whereas it produced additional migration at the wall. With these terms added in the model, the number density distributions of the particles and RBCs showed reasonable agreement with those of the measurement. Especially, the number of peaks and their location for the maximum values in the model and measurement matched well. |
著作権等: | Published under license by AIP Publishing The full-text file will be made open to the public on 23 August 2020 in accordance with publisher's 'Terms and Conditions for Self-Archiving'. この論文は出版社版でありません。引用の際には出版社版をご確認ご利用ください。 This is not the published version. Please cite only the published version. |
URI: | http://hdl.handle.net/2433/244133 |
DOI(出版社版): | 10.1063/1.5111201 |
出現コレクション: | 学術雑誌掲載論文等 |
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