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circrep.CR-19-0054.pdf | 665.31 kB | Adobe PDF | 見る/開く | |
1_CR-19-0054_1.pdf | Supplementary material | 983.55 kB | Adobe PDF | 見る/開く |
タイトル: | Association of Previous Hospitalization for Heart Failure With Increased Mortality in Patients Hospitalized for Acute Decompensated Heart Failure |
著者: | Su, Kanae Kato, Takao https://orcid.org/0000-0001-8213-7999 (unconfirmed) Toyofuku, Mamoru Morimoto, Takeshi Yaku, Hidenori Inuzuka, Yasutaka Tamaki, Yodo Ozasa, Neiko Yamamoto, Erika Yoshikawa, Yusuke Motohashi, Yasuyo Watanabe, Hiroki Kitai, Takeshi Taniguchi, Ryoji Iguchi, Moritake Kato, Masashi Nagao, Kazuya Kawai, Takafumi Komasa, Akihiro Nishikawa, Ryusuke Kawase, Yuichi Morinaga, Takashi Jinnai, Toshikazu Kawato, Mitsunori Sato, Yukihito Kuwahara, Koichiro Tamura, Takashi Kimura, Takeshi |
著者名の別形: | 加藤, 貴雄 小笹, 寧子 山本, 絵里香 芳川, 裕亮 木村, 剛 |
キーワード: | Heart failure Hospitalization Mortality |
発行日: | 8-Nov-2019 |
出版者: | Japanese Circulation Society |
誌名: | Circulation Reports |
巻: | 1 |
号: | 11 |
開始ページ: | 517 |
終了ページ: | 524 |
抄録: | Background: We sought to explore the effects of previous heart failure (HF) hospitalization on mortality in patients hospitalized for acute decompensated HF (ADHF) in a large Japanese contemporary observational database. Methods and Results: We prospectively enrolled consecutive patients with ADHF in 19 participating hospitals between October 2014 and March 2016. Of 4, 056 patients, 1, 442 patients (35.4%) had at least 1 previous HF hospitalization (previous hospitalization group), while 2, 614 patients (64.5%) did not have a history of HF hospitalization (de novo hospitalization group). Patients with previous hospitalization were older and more often had comorbidities such as anemia, and renal failure than those without. The cumulative 1-year incidence of all-cause death was significantly higher in the previous hospitalization group than in the de novo hospitalization group (28% vs. 19%, P<0.001). After adjusting confounders, the excess risk of the previous hospitalization group relative to the de novo hospitalization group for all-cause death remained significant (HR, 1.28; 95% CI: 1.10–1.50, P=0.001). The excess risk was significant in patients without advanced age, anemia, or renal failure, but not significant in patients with these comorbidities, with significant interaction. Increase in the number of hospitalizations was associated with an increased risk for mortality. Conclusions: In a contemporary ADHF cohort in Japan, repeated hospitalization was associated with an increasing, higher risk for 1-year mortality. |
著作権等: | © 2019 THE JAPANESE CIRCULATION SOCIETY 発行元の許可を得て掲載しています。 |
URI: | http://hdl.handle.net/2433/245134 |
DOI(出版社版): | 10.1253/circrep.CR-19-0054 |
PubMed ID: | 33693094 |
出現コレクション: | 学術雑誌掲載論文等 |
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