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Title: 前立腺癌治療中の前立腺再生検で診断した神経内分泌癌に対して集学的治療が奏効した1例
Other Titles: A Case of Neuroendcrine Carcinoma of the Prostate Diagnosed by Prostate Re-Biopsy during Hormonal Treatment and Effectively Treated by Multidisciplinary Therapy
Authors: 木村, 翔一  KAKEN_name
寺田, 直樹  KAKEN_name
秋岡, 貴弘  KAKEN_name
中原, 智子  KAKEN_name
長野, 正史  KAKEN_name
山本, 昇士  KAKEN_name
秋山, 裕  KAKEN_name
佐藤, 勇一郎  KAKEN_name
大塚, 武  KAKEN_name
木村, 友哉  KAKEN_name
飛田, 卓哉  KAKEN_name
岡部, 洸  KAKEN_name
高森, 大樹  KAKEN_name
木田, 和貴  KAKEN_name
上村, 敏雄  KAKEN_name
向井, 尚一郎  KAKEN_name
賀本, 敏行  KAKEN_name
Author's alias: Kimura, Shoichi
Terada, Naoki
Akioka, Takahiro
Nakahara, Tomoko
Nagano, Masahumi
Yamamoto, Koji
Akiyama, Yutaka
Sato, Yuichiro
Otsuka, Isamu
Kimura, Tomoya
Hida, Takuya
Okabe, Ko
Takamori, Hiroki
Kida, Kazutaka
Kamimura, Toshio
Mukai, Shoichiro
Kamoto, Toshiyuki
Keywords: Prostate cancer
Neuroendocrine prostate cancer
Radiation therapy
Issue Date: 31-Mar-2020
Publisher: 泌尿器科紀要刊行会
Journal title: 泌尿器科紀要 = Acta urologica Japonica
Volume: 66
Issue: 3
Start page: 91
End page: 96
Abstract: A 73-year-old Japanese man visited the urology clinic with the chief complaint of gross hematuria in June 2015. His prostate specific antigen (PSA) level was 146.7 ng/ml and he was diagnosed with prostate adenocarcinoma with a Gleason Score of 5+4. With bone metastasis in the right femur (cT3aN0M1), he was treated by orchiectomy and bicalutamide. He had gross hematuria in October 2017 and a prostate tumor was detected by computed tomography (CT) and magnetic resonance imaging without increasing PSA levels. Prostate re-biopsy showed prostate neuroendocrine carcinoma and local radiation therapy (74 Gy) was performed. Follow-up CT revealed a left adrenal tumor with a positive positron emission tomographic scan in October 2018. Under the diagnosis of metastatic neuroendocrine carcinoma, chemotherapy using cisplatinum and etoposide was performed. The tumor shrunk after five courses of treatment, followed by regrowth in April 2019. Radiation therapy (50 Gy) was added to the left adrenal tumor and it shrunk again. However, a left retroperitoneal tumor was detected in July 2019 and it was resected under laparoscopic surgery and diagnosed as metastatic neuroendocrine carcinoma. Since then, no recurrence has been observed.
Rights: 許諾条件により本文は2021/04/01に公開
DOI: 10.14989/ActaUrolJap_66_3_91
PubMed ID: 32316705
Appears in Collections:Vol.66 No.3

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