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タイトル: | A marine photosynthetic microbial cell factory as a platform for spider silk production |
著者: | Foong, Choon Pin Higuchi-Takeuchi, Mieko Malay, Ali D. Oktaviani, Nur Alia Thagun, Chonprakun Numata, Keiji ![]() ![]() ![]() |
著者名の別形: | フーン, チューン・ピン 樋口, 美栄子 沼田, 圭司 |
キーワード: | Applied microbiology Biomaterials - proteins |
発行日: | 8-Jul-2020 |
出版者: | Springer Nature |
誌名: | Communications Biology |
巻: | 3 |
論文番号: | 357 |
抄録: | Photosynthetic microorganisms such as cyanobacteria, purple bacteria and microalgae have attracted great interest as promising platforms for economical and sustainable production of bioenergy, biochemicals, and biopolymers. Here, we demonstrate heterotrophic production of spider dragline silk proteins, major ampullate spidroins (MaSp), in a marine photosynthetic purple bacterium, Rhodovulum sulfidophilum, under both photoheterotrophic and photoautotrophic growth conditions. Spider silk is a biodegradable and biocompatible material with remarkable mechanical properties. R. sulfidophilum grow by utilizing abundant and renewable nonfood bioresources such as seawater, sunlight, and gaseous CO2 and N2, thus making this photosynthetic microbial cell factory a promising green and sustainable production platform for proteins and biopolymers, including spider silks. |
記述: | 光合成細菌を用いてクモ糸を作ることに成功 --天然資源を利用した物質生産のモデル微生物--. 京都大学プレスリリース. 2020-07-13. |
著作権等: | © The Author(s) 2020. This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/. |
URI: | http://hdl.handle.net/2433/252537 |
DOI(出版社版): | 10.1038/s42003-020-1099-6 |
PubMed ID: | 32641733 |
関連リンク: | https://www.kyoto-u.ac.jp/ja/research-news/2020-07-13-1 |
出現コレクション: | 学術雑誌掲載論文等 |

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