Downloads: 29

Files in This Item:
File Description SizeFormat 
cga.12381.pdf226.99 kBAdobe PDFView/Open
Title: Current status and legal/ethical problems in the research use of the tissues of aborted human fetuses in Japan
Authors: Kawasaki, Hidenori  kyouindb  KAKEN_id
Yamada, Takahiro
Wada, Takahito
Kosugi, Shinji  kyouindb  KAKEN_id  orcid (unconfirmed)
Author's alias: 川崎, 秀徳
山田, 崇弘
和田, 敬仁
小杉, 眞司
Keywords: ELSI
fetal tissue
legal/ethical problem
Issue Date: Nov-2020
Publisher: Wiley
Journal title: Congenital anomalies
Volume: 60
Start page: 166
End page: 174
Abstract: To date, there is no law regulating the research use of human aborted fetuses in Japan. The aim was to review the current status with historical background and legal/ethical problems limiting the research use of the tissues of aborted human fetuses. We reviewed literature via PubMed, Web of Science, Scopus, Japana Centra Revuo Medicina and CiNii, reports from various committees and research groups from Ministry of Health, Labour and Welfare (MHLW), and domestic books. Aborted human fetal tissues used for research purposes were first documented in the 1920s. The first guideline, the Peel Code was released in 1972. Since then, in Western countries, the research use of aborted fetuses has been less restricted compared with that of embryos, due to the following guidelines outlined by expert groups. Currently, aborted fetal tissues are commercially available for research purposes in the United States. In Japan, only four indications are presented in “a public statement permitting research use of deceased fetuses' and ‘neonates’ organs, etc.” (1987). In the 2000s, expert committees of the MHLW concluded that research use of human aborted fetuses should be discontinued, and that comprehensive rules and independent regulations should be implemented. This issue has not been discussed in the Japanese legislature since 2003. Establishment of laws and guidelines for this issue is insufficient not only in Japan but also in other countries. It is important to secure transparency for making laws and guidelines and in obtaining public understanding.
Rights: This is the peer reviewed version of the following article: ['Congenital anomalies', 60(6), 166-174], which has been published in final form at This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions.
The full-text file will be made open to the public on 14 August 2021 in accordance with publisher's 'Terms and Conditions for Self-Archiving'
This is not the published version. Please cite only the published version.
DOI(Published Version): 10.1111/cga.12381
PubMed ID: 32572995
Appears in Collections:Journal Articles

Show full item record

Export to RefWorks

Export Format: 

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.