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Title: Effect of a 2.45-GHz radiofrequency electromagnetic field on neutrophil chemotaxis and phagocytosis in differentiated human HL-60 cells
Authors: Koyama, Shin  kyouindb  KAKEN_id
Narita, Eijiro
Suzuki, Yoshihisa
Taki, Masao
Shinohara, Naoki
Miyakoshi, Junji  kyouindb  KAKEN_id
Author's alias: 宮越, 順二
Keywords: radiofrequency (RF)
immune response
neutrophil
chemotaxis
phagocytosis
Issue Date: Jan-2015
Publisher: Oxford University Press (OUP)
Journal title: Journal of Radiation Research
Volume: 56
Issue: 1
Start page: 30
End page: 36
Abstract: The potential public health risks of radiofrequency (RF) fields have been discussed at length, especially with the use of mobile phones spreading extensively throughout the world. In order to investigate the properties of RF fields, we examined the effect of 2.45-GHz RF fields at the specific absorption rate (SAR) of 2 and 10 W/kg for 4 and 24 h on neutrophil chemotaxis and phagocytosis in differentiated human HL-60 cells. Neutrophil chemotaxis was not affected by RF-field exposure, and subsequent phagocytosis was not affected either compared with that under sham exposure conditions. These studies demonstrated an initial immune response in the human body exposed to 2.45-GHz RF fields at the SAR of 2 W/kg, which is the maximum value recommended by the International Commission for Non-Ionizing Radiation Protection (ICNIRP) guidelines. The results of our experiments for RF-field exposure at an SAR under 10 W/kg showed very little or no effects on either chemotaxis or phagocytosis in neutrophil-like human HL-60 cells.
Rights: © The Author 2014. Published by Oxford University Press on behalf of The Japan Radiation Research Society and Japanese Society for Radiation Oncology. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.
URI: http://hdl.handle.net/2433/260591
DOI(Published Version): 10.1093/jrr/rru075
PubMed ID: 25194051
Appears in Collections:Journal Articles

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