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Accurate determination of S-phase fraction in proliferative cells by dual fluorescence and peroxidase immunohistochemistry with 5-bromo-2'-deoxyuridine (BrdU) and Ki67 antibodies. Tanaka, Rina; Tainaka, Motomi; Ota, Takumi; Mizuguchi, Naoki; Kato, Hiroyuki; Urabe, Shoichi; Chen, Yulin; Fustin, Jean-Michel; Yamaguchi, Yoshiaki; Doi, Masao; Hamada, Shinshichi; Okamura, Hitoshi (2011-08) The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, 59(8): 791-798
Isoform-specific monoclonal antibodies against 3β-hydroxysteroid dehydrogenase/isomerase family provide markers for subclassification of human primary aldosteronism. Doi, Masao; Satoh, Fumitoshi; Maekawa, Takashi; Nakamura, Yasuhiro; Fustin, Jean-Michel; Tainaka, Motomi; Hotta, Yunhong; Takahashi, Yukari; Morimoto, Ryo; Takase, Kei; Ito, Sadayoshi; Sasano, Hironobu; Okamura, Hitoshi (2013-12-19) The Journal of clinical endocrinology and metabolism, 99(2): E257-E262
Circadian regulation of intracellular G-protein signalling mediates intercellular synchrony and rhythmicity in the suprachiasmatic nucleus. Doi, Masao; Ishida, Atsushi; Miyake, Akiko; Sato, Miho; Komatsu, Rie; Yamazaki, Fumiyoshi; Kimura, Ikuo; Tsuchiya, Soken; Kori, Hiroshi; Seo, Kazuyuki; Yamaguchi, Yoshiaki; Matsuo, Masahiro; Fustin, Jean-Michel; Tanaka, Rina; Santo, Yasuko; Yamada, Hiroyuki; Takahashi, Yukari; Araki, Michihiro; Nakao, Kazuki; Aizawa, Shinichi; Kobayashi, Masaki; Obrietan, Karl; Tsujimoto, Gozoh; Okamura, Hitoshi (2011-05-24) Nature communications, 2
Rhythmic Nucleotide Synthesis in the Liver: Temporal Segregation of Metabolites Fustin, Jean-Michel; Doi, Masao; Yamada, Hiroyuki; Komatsu, Rie; Shimba, Shigeki; Okamura, Hitoshi (2012-04) Cell Reports, 1(4): 341-349
Two Ck1δ transcripts regulated by m6A methylation code for two antagonistic kinases in the control of the circadian clock Fustin, Jean-Michel; Kojima, Rika; Itoh, Kakeru; Chang, Hsin-Yi; Shiqi, Ye; Zhuang, Bowen; Oji, Asami; Gibo, Shingo; Narasimamurthy, Rajesh; Virshup, David; Kurosawa, Gen; Doi, Masao; Manabe, Ichiro; Ishihama, Yasushi; Ikawa, Masahito; Okamura, Hitoshi (2018-06-05) Proceedings of the National Academy of Sciences, 115(23): 5980-5985
CK1δ/ε protein kinase primes the PER2 circadian phosphoswitch Narasimamurthy, Rajesh; Hunt, Sabrina R.; Lu, Yining; Fustin, Jean-Michel; Okamura, Hitoshi; Partch, Carrie L.; Forger, Daniel B.; Kim, Jae Kyoung; Virshup, David M. (2018-05-16) National Academy of Sciences
Circadian clock regulates hepatic polyploidy by modulating Mkp1-Erk1/2 signaling pathway Chao, Hsu-Wen; Doi, Masao; Fustin, Jean-Michel; Chen, Huatao; Murase, Kimihiko; Maeda, Yuki; Hayashi, Hida; Tanaka, Rina; Sugawa, Maho; Mizukuchi, Naoki; Yamaguchi, Yoshiaki; Yasunaga, Jun-ichirou; Matsuoka, Masao; Sakai, Mashito; Matsumoto, Michihiro; Hamada, Shinshichi; Okamura, Hitoshi (2017-12-21) Nature Communications, 8
Methylation deficiency disrupts biological rhythms from bacteria to humans Fustin, Jean-Michel; Ye, Shiqi; Rakers, Christin; Kaneko, Kensuke; Fukumoto, Kazuki; Yamano, Mayu; Versteven, Marijke; Grünewald, Ellen; Cargill, Samantha J.; Tamai, T. Katherine; Xu, Yao; Jabbur, Maria Luísa; Kojima, Rika; Lamberti, Melisa L.; Yoshioka-Kobayashi, Kumiko; Whitmore, David; Tammam, Stephanie; Howell, P. Lynne; Kageyama, Ryoichiro; Matsuo, Takuya; Stanewsky, Ralf; Golombek, Diego A.; Johnson, Carl Hirschie; Kakeya, Hideaki; van Ooijen, Gerben; Okamura, Hitoshi (2020-05-06) Communications Biology, 3
Non-coding cis-element of Period2 is essential for maintaining organismal circadian behaviour and body temperature rhythmicity Doi, Masao; Shimatani, Hiroyuki; Atobe, Yuta; Murai, Iori; Hayashi, Hida; Takahashi, Yukari; Fustin, Jean-Michel; Yamaguchi, Yoshiaki; Kiyonari, Hiroshi; Koike, Nobuya; Yagita, Kazuhiro; Lee, Choogon; Abe, Manabu; Sakimura, Kenji; Okamura, Hitoshi (2019-06-12) Nature Communications, 10
Excess S-adenosylmethionine inhibits methylation via catabolism to adenine Fukumoto, Kazuki; Ito, Kakeru; Saer, Benjamin; Taylor, George; Ye, Shiqi; Yamano, Mayu; Toriba, Yuki; Hayes, Andrew; Okamura, Hitoshi; Fustin, Jean-Michel (2022) Communications Biology, 5