ダウンロード数: 307
このアイテムのファイル:
ファイル | 記述 | サイズ | フォーマット | |
---|---|---|---|---|
67_5_197.pdf | 844.4 kB | Adobe PDF | 見る/開く |
タイトル: | 膵頭十二指腸浸潤による難治性消化管出血を伴う転移性腎細胞癌に対して全身治療後に原発巣摘除を行い完全寛解が得られた1例 |
その他のタイトル: | Complete Remission of Metastatic Renal Cell Carcinoma with Invasion of the Duodenum and Pancreas after Treatment with Nivolumab Plus Ipilimumab Followed by Axitinib and Surgery : A Case Report |
著者: | 萩本, 裕樹 山﨑, 俊成 嘉島, 相輝 吉野, 喬之 後藤, 崇之 佐野, 剛視 澤田, 篤郎 赤松, 秀輔 小林, 恭 仲野, 健三 八木, 真太郎 松岡, 由 藤本, 正数 https://orcid.org/0000-0002-0575-6507 (unconfirmed) 北村, 貴明 小川, 修 |
著者名の別形: | HAGIMOTO, Hiroki YAMAZAKI, Toshinari KASHIMA, Soki YOSHINO, Takayuki GOTO, Takayuki SANO, Takeshi SAWADA, Atsuro AKAMATSU, Shusuke KOBAYASHI, Takashi NAKANO, Kenzo YAGI, Shintaro MATSUOKA, Yui FUJIMOTO, Masakazu KITAMURA, Takaaki OGAWA, Osamu |
キーワード: | Renal cell carcinoma Duodenal bleeding Immune checkpoint inhibitor Anti-angiogenic therapy |
発行日: | 31-May-2021 |
出版者: | 泌尿器科紀要刊行会 |
誌名: | 泌尿器科紀要 |
巻: | 67 |
号: | 5 |
開始ページ: | 197 |
終了ページ: | 203 |
抄録: | A man in his 60s was diagnosed with clear cell carcinoma of the right kidney with multiple lung metastases, tumor thrombus of the inferior vena cava (IVC), and invasion of the duodenum and pancreas. Ipilimumab plus nivolumab was administered as first-line therapy. After 3 treatment courses, computed tomography (CT) demonstrated a slight decrease in the size of the primary tumor and lung metastases. However, the patient became hemodynamically unstable due to persistent duodenal bleeding during treatment despite frequent blood transfusions. Axitinib was then initiated as second-line therapy. The duodenal bleeding ceased 10 days after starting axitinib and his anemia remissed. Subsequent CT showed further decrease in the size of the primary tumor and lung metastases. The patient underwent right nephrectomy after improvement of nutrition. IVC thrombectomy, and pancreaticoduodenectomy. The lung metastases disappeared on postoperative imaging and no additional treatment was provided. Twelve months after surgery, he was in good health and showed no signs of recurrence. |
著作権等: | 許諾条件により本文は2022-06-01に公開 |
DOI: | 10.14989/ActaUrolJap_67_5_197 |
URI: | http://hdl.handle.net/2433/263323 |
PubMed ID: | 34126663 |
出現コレクション: | Vol.67 No.5 |
このリポジトリに保管されているアイテムはすべて著作権により保護されています。