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タイトル: Admission systolic blood pressure as a prognostic predictor of acute decompensated heart failure: A report from the KCHF registry
著者: Kawase, Yuichi
Kato, Takao  kyouindb  KAKEN_id  orcid https://orcid.org/0000-0001-8213-7999 (unconfirmed)
Morimoto, Takeshi
Hata, Reo
Murai, Ryosuke
Tada, akeshi
Katoh, Harumi
Kadota, Kazushige
Yamamoto, Erika  kyouindb  KAKEN_id
Yaku, Hidenori
Inuzuka, Yasutaka
Tamaki, Yodo
Ozasa, Neiko
Yoshikawa, Yusuke
Iguchi, Moritake
Nagao, Kazuya
Sato, Yukihito
Kuwahara, Koichiro
Kimura, Takeshi
著者名の別形: 加藤, 貴雄
畑, 玲央
山本, 絵里香
夜久, 英憲
小笹, 寧子
芳川, 裕亮
木村, 剛
キーワード: Heart failure
Blood pressure
Hypertension
Ejection fraction
Medical risk factors
Enzyme inhibitors
Prognosis
Cardiovascular disease risk
発行日: Jul-2021
出版者: Public Library of Science (PLoS)
誌名: PLOS One
巻: 16
号: 7
論文番号: e0253999
抄録: [Background] Admission systolic blood pressure has emerged as a predictor of postdischarge outcomes of patients with acute decompensated heart failure; however, its validity in varied clinical conditions of this patient subset is unclear. The aim of this study was to further explore the prognostic value of admission systolic blood pressure in patients with acute decompensated heart failure. [Methods] The Kyoto Congestive Heart Failure (KCHF) registry is a prospective, observational, multicenter cohort study enrolling consecutive patients with acute decompensated heart failure from 19 participating hospitals in Japan. Clinical characteristics at baseline and prognosis were examined by the following value range of admission systolic blood pressure: <100, 100–139, and ≥140 mmHg. The primary outcome measure was defined as all-cause death after discharge. Subgroup analyses were done for prior hospitalization for heart failure, hypertension, left ventricular ejection fraction, and medications at discharge. We excluded patients with acute coronary syndrome or insufficient data. [Results] We analyzed 3564 patients discharged alive out of 3804 patients hospitalized for acute decompensated heart failure. In the entire cohort, lower admission systolic blood pressure was associated with poor outcomes (1-year cumulative incidence of all-cause death: <100 mmHg, 26.8%; 100–139 mmHg, 20.2%; and ≥140 mmHg, 15.1%, p<0.001). The magnitude of the effect of lower admission systolic blood pressure for postdischarge all-cause death was greater in patients with prior hospitalization for heart failure, heart failure with reduced left ventricular ejection fraction, and β-blocker use at discharge than in those without. [Conclusions] Admission systolic blood pressure is useful for postdischarge risk stratification in patients with acute decompensated heart failure. Its magnitude of the effect as a prognostic predictor may differ across clinical conditions of patients.
著作権等: © 2021 Kawase et al.
This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
URI: http://hdl.handle.net/2433/265356
DOI(出版社版): 10.1371/journal.pone.0253999
PubMed ID: 34214124
出現コレクション:学術雑誌掲載論文等

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