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dc.contributor.author | Hu, Naonori | en |
dc.contributor.author | Tanaka, Hiroki | en |
dc.contributor.author | Kakino, Ryo | en |
dc.contributor.author | Yoshikawa, Syuushi | en |
dc.contributor.author | Miyao, Mamoru | en |
dc.contributor.author | Akita, Kazuhiko | en |
dc.contributor.author | Isohashi, Kayako | en |
dc.contributor.author | Aihara, Teruhito | en |
dc.contributor.author | Nihei, Keiji | en |
dc.contributor.author | Ono, Koji | en |
dc.contributor.alternative | 呼, 尚徳 | ja |
dc.contributor.alternative | 田中, 浩基 | ja |
dc.date.accessioned | 2022-07-29T00:47:56Z | - |
dc.date.available | 2022-07-29T00:47:56Z | - |
dc.date.issued | 2021 | - |
dc.identifier.uri | http://hdl.handle.net/2433/275655 | - |
dc.description.abstract | Boron neutron capture therapy (BNCT) for the treatment of unresectable, locally advanced, and recurrent carcinoma of the head and neck cancer has been approved by the Japanese government for reimbursement under the national health insurance as of June 2020. A new treatment planning system for clinical BNCT has been developed by Sumitomo Heavy Industries, Ltd. (Sumitomo), NeuCure® Dose Engine. To safely implement this system for clinical use, the simulated neutron flux and gamma ray dose rate inside a water phantom was compared against experimental measurements. Furthermore, to validate and verify the new planning system, the dose distribution inside an anthropomorphic head phantom was compared against a BNCT treatment planning system SERA and an in-house developed Monte Carlo dose calculation program. The simulated results closely matched the experimental results, within 5% for the thermal neutron flux and 10% for the gamma ray dose rate. The dose distribution inside the head phantom closely matched with SERA and the in-house developed dose calculation program, within 3% for the tumour and a difference of 0.3 Gyw for the brain. | en |
dc.language.iso | eng | - |
dc.publisher | Springer Nature | en |
dc.publisher | BMC | en |
dc.rights | © The Author(s) 2021 | en |
dc.rights | This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. | en |
dc.rights.uri | http://creativecommons.org/licenses/by/4.0/ | - |
dc.subject | Boron neutron capture therapy | en |
dc.subject | Treatment planning system | en |
dc.subject | Commissioning | en |
dc.subject | Monte Carlo simulation | en |
dc.title | Evaluation of a treatment planning system developed for clinical boron neutron capture therapy and validation against an independent Monte Carlo dose calculation system | en |
dc.type | journal article | - |
dc.type.niitype | Journal Article | - |
dc.identifier.jtitle | Radiation Oncology | en |
dc.identifier.volume | 16 | - |
dc.relation.doi | 10.1186/s13014-021-01968-2 | - |
dc.textversion | publisher | - |
dc.identifier.artnum | 243 | - |
dc.identifier.pmid | 34952608 | - |
dcterms.accessRights | open access | - |
dc.identifier.eissn | 1748-717X | - |
出現コレクション: | 学術雑誌掲載論文等 |
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