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このアイテムのファイル:
| ファイル | 記述 | サイズ | フォーマット | |
|---|---|---|---|---|
| j.cmet.2021.12.008.pdf | 823.23 kB | Adobe PDF | 見る/開く |
| タイトル: | Targeting p21 for diabetes: Another choice of senotherapy |
| 著者: | Kondoh, Hiroshi   Hara, Eiji |
| 著者名の別形: | 近藤, 祥司 |
| 発行日: | 4-Jan-2022 |
| 出版者: | Elsevier BV Cell Press |
| 誌名: | Cell Metabolism |
| 巻: | 34 |
| 号: | 1 |
| 開始ページ: | 5 |
| 終了ページ: | 7 |
| 抄録: | Senotherapy, the elimination of senescent cells, is a cutting-edge treatment for aging-related and lifestyle diseases. In this issue of Cell Metabolism, Wang et al. report that p21[Cip1] highly expressing cells, which represent a senescent cell population, occur in the adipose tissue during obesity. Targeting them genetically or pharmacologically attenuates insulin resistance, suggesting a possible therapeutic approach to treat the metabolic complications of obesity. |
| 著作権等: | © 2021. This manuscript version is made available under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International license. The full-text file will be made open to the public on 4 January 2023 in accordance with publisher's 'Terms and Conditions for Self-Archiving'. This is not the published version. Please cite only the published version. この論文は出版社版でありません。引用の際には出版社版をご確認ご利用ください。 |
| URI: | http://hdl.handle.net/2433/275959 |
| DOI(出版社版): | 10.1016/j.cmet.2021.12.008 |
| PubMed ID: | 34986338 |
| 出現コレクション: | 学術雑誌掲載論文等 |
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