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タイトル: | Appropriate margin for planning target volume for breast radiotherapy during deep inspiration breath-hold by variance component analysis |
著者: | Ono, Yuka Yoshimura, Michio https://orcid.org/0000-0001-6665-2245 (unconfirmed) Ono, Tomohiro Fujimoto, Takahiro Miyabe, Yuki Matsuo, Yukinori https://orcid.org/0000-0002-4372-8259 (unconfirmed) Mizowaki, Takashi https://orcid.org/0000-0002-8135-8746 (unconfirmed) |
著者名の別形: | 小野, 幸果 吉村, 通央 小野, 智博 藤本, 隆広 宮部, 結城 松尾, 幸憲 溝脇, 尚志 |
キーワード: | Breast cancer Deep inspiration breath-hold Cine electronic portal imaging device Inter-patient Inter-fraction Intra-fraction Planning target volume margin |
発行日: | 2021 |
出版者: | Springer Nature BMC |
誌名: | Radiation Oncology |
巻: | 16 |
論文番号: | 49 |
抄録: | BACKGROUND: This study aimed to quantify errors by using a cine electronic portal imaging device (cine EPID) during deep inspiration breath-hold (DIBH) for left-sided breast cancer and to estimate the planning target volume (PTV) by variance component analysis. METHODS: This study included 25 consecutive left-sided breast cancer patients treated with whole-breast irradiation (WBI) using DIBH. Breath-holding was performed while monitoring abdominal anterior-posterior (AP) motion using the Real-time Position Management (RPM) system. Cine EPID was used to evaluate the chest wall displacements in patients. Cine EPID images of the patients (309, 609 frames) were analyzed to detect the edges of the chest wall using a Canny filter. The errors that occurred during DIBH included differences between the chest wall position detected by digitally reconstructed radiographs and that of all cine EPID images. The inter-patient, inter-fraction, and intra-fractional standard deviations (SDs) in the DIBH were calculated, and the PTV margin was estimated by variance component analysis. RESULTS: The median patient age was 55 (35-79) years, and the mean irradiation time was 20.4 ± 1.7 s. The abdominal AP motion was 1.36 ± 0.94 (0.14-5.28) mm. The overall mean of the errors was 0.30 mm (95% confidence interval: - 0.05-0.65). The inter-patient, inter-fraction, and intra-fractional SDs in the DIBH were 0.82 mm, 1.19 mm, and 1.63 mm, respectively, and the PTV margin was calculated as 3.59 mm. CONCLUSIONS: Errors during DIBH for breast radiotherapy were monitored using EPID images and appropriate PTV margins were estimated by variance component analysis. |
著作権等: | © The Author(s) 2021. This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. |
URI: | http://hdl.handle.net/2433/276569 |
DOI(出版社版): | 10.1186/s13014-021-01777-7 |
PubMed ID: | 33676532 |
出現コレクション: | 学術雑誌掲載論文等 |
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