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タイトル: | Incidence and Clinical Features of Venous Thromboembolism in Hospitalized Patients With Coronavirus Disease 2019 (COVID-19) in Japan |
著者: | Yamashita, Yugo Maruyama, Yuuki Satokawa, Hirono Nishimoto, Yuji Tsujino, Ichizo Sakashita, Hideki Nakata, Hiroko Okuno, Yoshinori Ogihara, Yoshito Yachi, Sen Toya, Naoki Shingaki, Masami Ikeda, Satoshi Yamamoto, Naoto Aikawa, Shizu Ikeda, Nobutaka Hayashi, Hiroya Ishiguro, Shingo Iwata, Eriko Umetsu, Michihisa Kondo, Akane Iwai, Takehisa Kobayashi, Takao Mo, Makoto Yamada, Norikazu |
著者名の別形: | 山下, 侑吾 奥野, 善教 |
キーワード: | Asians Coronavirus disease 2019 (COVID-19) Japan Pulmonary embolism Venous thromboembolism |
発行日: | 25-Nov-2021 |
出版者: | Japanese Circulation Society |
誌名: | Circulation Journal |
巻: | 85 |
号: | 12 |
開始ページ: | 2208 |
終了ページ: | 2214 |
抄録: | BACKGROUND: Coronavirus disease 2019 (COVID-19) reportedly causes venous thromboembolism (VTE), but the status of this complication in Japan was unclear.Methods and Results:The VTE and COVID-19 in Japan Study is a retrospective, multicenter cohort study enrolling hospitalized patients with COVID-19 who were evaluated with contrast-enhanced computed tomography (CT) examination at 22 centers in Japan between March 2020 and October 2020. Among 1, 236 patients with COVID-19, 45 (3.6%) were evaluated with contrast-enhanced CT examination. VTE events occurred in 10 patients (22.2%), and the incidence of VTE in mild, moderate, and severe COVID-19 was 0%, 11.8%, and 40.0%, respectively. COVID-19 patients with VTE showed a higher body weight (81.6 vs. 64.0 kg, P=0.005) and body mass index (26.9 vs. 23.2 kg/m2, P=0.04), and a higher proportion had a severe status for COVID-19 compared with those without. There was no significant difference in the proportion of patients alive at discharge between patients with and without VTE (80.0% vs. 88.6%, P=0.48). Among 8 pulmonary embolism (PE) patients, all were low-risk PE. CONCLUSIONS: Among a relatively small number of patients undergoing contrast-enhanced CT examination in Japanese real-world clinical practice, there were no VTE patients among those with mild COVID-19, but the incidence of VTE seemed to be relatively high among severe COVID-19 patients, although all PE events were low-risk without significant effect on mortality risk. |
著作権等: | © 2021, THE JAPANESE CIRCULATION SOCIETY This article is licensed under a Creative Commons [Attribution-NonCommercial-NoDerivatives 4.0 International] license. |
URI: | http://hdl.handle.net/2433/276999 |
DOI(出版社版): | 10.1253/circj.CJ-21-0169 |
PubMed ID: | 34011824 |
出現コレクション: | 学術雑誌掲載論文等 |
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