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タイトル: Incidence and Clinical Features of Venous Thromboembolism in Hospitalized Patients With Coronavirus Disease 2019 (COVID-19) in Japan
著者: Yamashita, Yugo  kyouindb  KAKEN_id
Maruyama, Yuuki
Satokawa, Hirono
Nishimoto, Yuji
Tsujino, Ichizo
Sakashita, Hideki
Nakata, Hiroko
Okuno, Yoshinori
Ogihara, Yoshito
Yachi, Sen
Toya, Naoki
Shingaki, Masami
Ikeda, Satoshi
Yamamoto, Naoto
Aikawa, Shizu
Ikeda, Nobutaka
Hayashi, Hiroya
Ishiguro, Shingo
Iwata, Eriko
Umetsu, Michihisa
Kondo, Akane
Iwai, Takehisa
Kobayashi, Takao
Mo, Makoto
Yamada, Norikazu
著者名の別形: 山下, 侑吾
奥野, 善教
キーワード: Asians
Coronavirus disease 2019 (COVID-19)
Japan
Pulmonary embolism
Venous thromboembolism
発行日: 25-Nov-2021
出版者: Japanese Circulation Society
誌名: Circulation Journal
巻: 85
号: 12
開始ページ: 2208
終了ページ: 2214
抄録: BACKGROUND: Coronavirus disease 2019 (COVID-19) reportedly causes venous thromboembolism (VTE), but the status of this complication in Japan was unclear.Methods and Results:The VTE and COVID-19 in Japan Study is a retrospective, multicenter cohort study enrolling hospitalized patients with COVID-19 who were evaluated with contrast-enhanced computed tomography (CT) examination at 22 centers in Japan between March 2020 and October 2020. Among 1, 236 patients with COVID-19, 45 (3.6%) were evaluated with contrast-enhanced CT examination. VTE events occurred in 10 patients (22.2%), and the incidence of VTE in mild, moderate, and severe COVID-19 was 0%, 11.8%, and 40.0%, respectively. COVID-19 patients with VTE showed a higher body weight (81.6 vs. 64.0 kg, P=0.005) and body mass index (26.9 vs. 23.2 kg/m2, P=0.04), and a higher proportion had a severe status for COVID-19 compared with those without. There was no significant difference in the proportion of patients alive at discharge between patients with and without VTE (80.0% vs. 88.6%, P=0.48). Among 8 pulmonary embolism (PE) patients, all were low-risk PE. CONCLUSIONS: Among a relatively small number of patients undergoing contrast-enhanced CT examination in Japanese real-world clinical practice, there were no VTE patients among those with mild COVID-19, but the incidence of VTE seemed to be relatively high among severe COVID-19 patients, although all PE events were low-risk without significant effect on mortality risk.
著作権等: © 2021, THE JAPANESE CIRCULATION SOCIETY
This article is licensed under a Creative Commons [Attribution-NonCommercial-NoDerivatives 4.0 International] license.
URI: http://hdl.handle.net/2433/276999
DOI(出版社版): 10.1253/circj.CJ-21-0169
PubMed ID: 34011824
出現コレクション:学術雑誌掲載論文等

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