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このアイテムのファイル:
| ファイル | 記述 | サイズ | フォーマット | |
|---|---|---|---|---|
| j.scr.2021.102274.pdf | 2.77 MB | Adobe PDF | 見る/開く |
| タイトル: | Human induced pluripotent stem cells generated from a patient with idiopathic basal ganglia calcification |
| 著者: | Yada, Yuichiro Kondo, Takayuki Suga, Mika Tsukita, Kayoko Enami, Takako Shibukawa, Ran Sagara, Yukako Okanishi, Yasue Imamura, Keiko   Kihara, Takeshi Inoue, Haruhisa  https://orcid.org/0000-0003-4736-9537 (unconfirmed) |
| 著者名の別形: | 矢田, 祐一郎 近藤, 孝之 菅, 三佳 月田, 香代子 江浪, 貴子 澁川, 蘭 佐柄, 友佳子 岡西, 泰永 今村, 恵子 井上, 治久 |
| 発行日: | May-2021 |
| 出版者: | Elsevier BV |
| 誌名: | Stem Cell Research |
| 巻: | 53 |
| 論文番号: | 102274 |
| 抄録: | Idiopathic basal ganglia calcification (IBGC) is a rare neurodegenerative disease, characterized by abnormal calcium deposits in basal ganglia of the brain. The affected individuals exhibit movement disorders, and progressive deterioration of cognitive and psychiatric ability. The genetic cause of the disease is mutation in one of several different genes, SLC20A2, PDGFB, PDGFRB, XPR1 or MYORG, which inheritably or sporadically occurs. Here we generated an induced pluripotent stem cell (iPSC) line from an IBGC patient, which is likely be a powerful tool for revealing the pathomechanisms and exploring potential therapeutic candidates of IBGC. |
| 著作権等: | © 2021 The Authors. Published by Elsevier B.V. This is an open access article under the CC BY-NC-ND license. |
| URI: | http://hdl.handle.net/2433/277026 |
| DOI(出版社版): | 10.1016/j.scr.2021.102274 |
| PubMed ID: | 33714066 |
| 出現コレクション: | 学術雑誌掲載論文等 |
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