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| ファイル | 記述 | サイズ | フォーマット | |
|---|---|---|---|---|
| j.xpro.2022.101484.pdf | 3.72 MB | Adobe PDF | 見る/開く |
| タイトル: | Protocol for the generation and expansion of human iPS cell-derived ureteric bud organoids |
| 著者: | Ryosaka, Makoto Mae, Shin-Ichi Osafune, Kenji    https://orcid.org/0000-0001-7238-2763 (unconfirmed) |
| 著者名の別形: | 兩坂, 誠 前, 伸一 長船, 健二 |
| キーワード: | Stem Cells Cell Differentiation Organoids |
| 発行日: | Sep-2022 |
| 出版者: | Elsevier BV |
| 誌名: | STAR Protocols |
| 巻: | 3 |
| 号: | 3 |
| 論文番号: | 101484 |
| 抄録: | The ureteric bud (UB) is a kidney precursor tissue that repeats branching morphogenesis and gives rise to the collecting ducts (CDs) and lower urinary tract. Here, we describe protocols to generate iUB organoids from human iPSCs; iUB organoids repeat branching morphogenesis. We describe how to expand iUB-organoid-derived tip colonies and how to induce CD progenitors from iUB organoids. These organoids can be used to study CD development and potentially as a model of kidney and urinary tract diseases. |
| 著作権等: | © 2022 The Author(s). This is an open access article under the CC BY license. |
| URI: | http://hdl.handle.net/2433/277472 |
| DOI(出版社版): | 10.1016/j.xpro.2022.101484 |
| PubMed ID: | 35769929 |
| 出現コレクション: | 学術雑誌掲載論文等 |
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