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タイトル: Sexual dimorphism of the human fetal pelvis exists at the onset of primary ossification
著者: Kanahashi, Toru  kyouindb  KAKEN_id  orcid https://orcid.org/0000-0002-9895-0500 (unconfirmed)
Matsubayashi, Jun
Imai, Hirohiko  KAKEN_id  orcid https://orcid.org/0000-0002-6957-0031 (unconfirmed)
Yamada, Shigehito  kyouindb  KAKEN_id  orcid https://orcid.org/0000-0002-8194-6927 (unconfirmed)
Otani, Hiroki
Takakuwa, Tetsuya  kyouindb  KAKEN_id  orcid https://orcid.org/0000-0002-9660-9384 (unconfirmed)
著者名の別形: 金橋, 徹
松林, 潤
今井, 宏彦
山田, 重人
大谷 浩
高桑, 徹也
キーワード: Bone
Cartilage
発行日: 7-May-2024
出版者: Springer Nature
誌名: Communications Biology
巻: 7
論文番号: 538
抄録: Human adolescent and adult skeletons exhibit sexual dimorphism in the pelvis. However, the degree of sexual dimorphism of the human pelvis during prenatal development remains unclear. Here, we performed high-resolution magnetic resonance imaging-assisted pelvimetry on 72 human fetuses (males [M]: females [F], 34:38; 21 sites) with crown-rump lengths (CRL) of 50–225 mm (the onset of primary ossification). We used multiple regression analysis to examine sexual dimorphism with CRL as a covariate. Females exhibit significantly smaller pelvic inlet anteroposterior diameters (least squares mean, [F] 8.4 mm vs. [M] 8.8 mm, P = 0.036), larger subpubic angle ([F] 68.1° vs. [M] 64.0°, P = 0.034), and larger distance between the ischial spines relative to the transverse diameters of the greater pelvis than males. Furthermore, the sacral measurements indicate significant sex-CRL interactions. Our study suggests that sexual dimorphism of the human fetal pelvis is already apparent at the onset of primary ossification.
記述: ヒト胎児の骨盤の性差は一次骨化が開始する受精後9週には既に存在する. 京都大学プレスリリース. 2024-05-20.
著作権等: © The Author(s) 2024
This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder.
URI: http://hdl.handle.net/2433/289130
DOI(出版社版): 10.1038/s42003-024-06156-y
PubMed ID: 38714799
関連リンク: https://www.kyoto-u.ac.jp/ja/research-news/2024-05-20-1
出現コレクション:学術雑誌掲載論文等

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