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タイトル: | Clinical implications of combination therapy with quizartinib and craniospinal irradiation for refractory acute myeloid leukemia positive for FMS-like tyrosine kinase 3-internal tandem duplication with central nervous system involvement |
著者: | Suga, Makiko Fukushima, Kentaro Ueda, Tomoaki Arai, Yasuyuki ![]() ![]() ![]() Nakagawa, Shunsaku Minami, Yosuke Toda, Jun Hino, Akihisa Fujita, Jiro Yokota, Takafumi Hosen, Naoki |
著者名の別形: | 新井, 康之 中川, 俊作 |
キーワード: | acute myeloid leukemia CNS involvement FLT3 inhibitor stem cell transplantation |
発行日: | Feb-2022 |
出版者: | Wiley |
誌名: | Clinical Case Reports |
巻: | 10 |
号: | 2 |
論文番号: | e05384 |
抄録: | FMS-like tyrosine kinase 3-internal tandem duplication (FLT3-ITD) mutation-positive acute myeloid leukemia (AML) has a poor prognosis. We report the first case of successful bridge therapy of novel FLT3 inhibitor, quizartinib, to umbilical cord blood stem cell transplantation for FLT3-ITD-positive AML-primary induction failure patients with central nervous system involvement. |
著作権等: | © 2022 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd. This is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made. |
URI: | http://hdl.handle.net/2433/293482 |
DOI(出版社版): | 10.1002/ccr3.5384 |
PubMed ID: | 35140970 |
出現コレクション: | 学術雑誌掲載論文等 |

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