前立腺肥大症に関する研究 第II篇:尿中酸フォスファターゼに關する研究(基礎的實験)

Abstract

The urinary acid phosphatase was examined by use of the modified method of Shinowara-Johnes Reinhart. The results were as follows: 1. It was recognized that the adult human male urine was rich in acid phosphatase, most of which orignated in the prostate gland. 2. The prostatic acid phosphatase was excreted into the urine no only during micturiation, but also a portion of the prostatic secretion became mixed with urine in the bladder even without micturiation. Therefore, it is assumed that there exists some transmission between the contents of the bladder and of the posterior urethra. 3.It seems that urinary acid phosphatase in the bladder becomes concentni.ted with presence of residual urine. 4. The amount of urinary acid phosphatase of the adult human male shows a great variation among individuals and daily even in the same individual. 5. It was considered that there was no definite correlation between the urinary acid phosphatase and the specific gravity of urine when the gravity ranged within 1012-1025. Urinary acid phosphatase did not seem to be affected by the concentration of Mg-Ion in the urine when the quantity of Mg-Ion was normal. 6. Formaline-resistant acid phosphatase was examined in ureteral (renal) urine, male-urine, female-urine, and child's urine; and the results showed only a little difference cetween them. Therefore, the results reported by King and his coworkers do not seem to be substantiated, that is, the formaline resistant acid phosphatase was not so specific for the prostatic acid phosphatase.