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DCフィールド | 値 | 言語 |
---|---|---|
dc.contributor.author | 稲田, 務 | ja |
dc.contributor.author | 酒徳, 治三郎 | ja |
dc.contributor.author | 沢西, 謙次 | ja |
dc.contributor.author | 田中, 正躬 | ja |
dc.contributor.author | 中川, 隆 | ja |
dc.contributor.alternative | INADA, Tsutomu | en |
dc.contributor.alternative | SAKATOKU, Jisaburo | en |
dc.contributor.alternative | SAWANISHI, Kenji | en |
dc.contributor.alternative | TANAKA, Masami | en |
dc.contributor.alternative | NAKAGAWA, Takashi | en |
dc.date.accessioned | 2010-05-19T08:23:53Z | - |
dc.date.available | 2010-05-19T08:23:53Z | - |
dc.date.issued | 1961-03 | - |
dc.identifier.issn | 0018-1994 | - |
dc.identifier.uri | http://hdl.handle.net/2433/112103 | - |
dc.description.abstract | 1) Chemical properties, antibacterial effects, blood and u r i nary concentrations, toxicities, and applications of nitrofuran derivatives, such as nitrofurazone (Furacin), G uanofuracin, Altafur, Furaspol, nifuroxime (Micofur), Furmethonol, furazolidone, and nitro f urantoin (Furadantin), being clinically employed have been presented. 2) Administration of furazolidone or Furadantin t o the patients with urinary tract infection has been attempted. When furazolido n e was administered to 7 patients with urinary tract infection, it was found that furazolidone was effective in 2 patients, fairly effective in 1 patient, futile in 3 patients, and unknown in 1 patient. Side effects along with administration of furazol i done, mainly gastric upset, were free in only 2 patients. However, it was found th a t slight side effect was found in 1 patient and moderate to severe side effect in 4 patients. There f ore, it is suggested that furazolidone produces poor therapeutic effect on urinary tract infection with high incidence of unpleasant side effects. When Furadantin was administered t o 19 patients with urinary tract infection, it was found that Furadantin was significantly effective in 3 patients, effective in 9 patients, fai r ly effective in 3 patients, futile in 1 patient, and unknown in 3 patients. It was observed that no side effect was found in 13 cases, slight side effect in 2 cases, and moderate to sev ere side effect in 4 cases. Furadantin possesses low toxicity and broad antimicrobial spe c trum with low incidence of appearance of resistant bacteria. It is also capable of a l o ng term administration of Furadantin and of easily reaching the effective urinary concentrat i on. Therefore, Furadantin is considered to be one of the satisfactorily effect i ve drugs for treatment of urinary tract infection. 3) According to the fa c t that nitrofuran derivatives, such as nitrofurazone etc., possesses antispermatogenetic action, the reports of administration of the drugs as a che m o therapeutic for testicular tumor were reviewed. The results of administration of nitrofurazone to 3 cases of testicular tumor were described. Unfortunately they were short term administrations. Therefore, it is necessary to obtain a large series with long term administration in order to get conclusion for effectiveness of nitrofurazone for testicular tumor. Furthermore, mechanism of action of nitrofurazone was discussed from a standpoint of histogenetic theory of testicular tumor. | en |
dc.format.mimetype | application/pdf | - |
dc.language.iso | jpn | - |
dc.publisher | 京都大学医学部泌尿器科教室 | ja |
dc.publisher.alternative | Department of Urology, Faculty of Medicine, Kyoto Univeersity | en |
dc.subject.ndc | 494.9 | - |
dc.title | Nitrofuran系化合物の使用経験(特にFuradantinによる尿路感染症治療を中心として) | ja |
dc.title.alternative | Trials with Nitrofuran Derivatives with a Special Reference to Treatment of Urinary Tract Infection | en |
dc.type | departmental bulletin paper | - |
dc.type.niitype | Departmental Bulletin Paper | - |
dc.identifier.ncid | AN00208315 | - |
dc.identifier.jtitle | 泌尿器科紀要 | ja |
dc.identifier.volume | 7 | - |
dc.identifier.issue | 3 | - |
dc.identifier.spage | 447 | - |
dc.identifier.epage | 477 | - |
dc.textversion | publisher | - |
dc.sortkey | 14 | - |
dc.address | 京都大学医学部泌尿器科教室 | ja |
dc.address | 京都大学医学部泌尿器科教室 | ja |
dc.address | 京都大学医学部泌尿器科教室 | ja |
dc.address | 京都大学医学部泌尿器科教室 | ja |
dc.address | 京都大学医学部泌尿器科教室 | ja |
dc.address.alternative | the Department of Urology, Faculty of Medicine, Kyoto University, Kyoto, Japan | en |
dc.address.alternative | the Department of Urology, Faculty of Medicine, Kyoto University, Kyoto, Japan | en |
dc.address.alternative | the Department of Urology, Faculty of Medicine, Kyoto University, Kyoto, Japan | en |
dc.address.alternative | the Department of Urology, Faculty of Medicine, Kyoto University, Kyoto, Japan | en |
dc.address.alternative | the Department of Urology, Faculty of Medicine, Kyoto University, Kyoto, Japan | en |
dcterms.accessRights | open access | - |
dc.identifier.pissn | 0018-1994 | - |
dc.identifier.jtitle-alternative | Acta urologica Japonica | la |
dc.identifier.jtitle-alternative | Hinyokika Kiyo | en |
出現コレクション: | Vol.7 No.3 |
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