真性半陰陽の2例

Abstract

Two cases of true hermaphroditism were presented. Case 1. A 5 year-old child, who was brou g ht up as a girl, was admitted for evaluation of her enlarged clitoris. Sex-chromatin pattern was female. Chromosomal investigation showed that the patient had 46 chromosoms with sex chromosom constitution of an XY. Both gonads were removed at laparotomy. Histological examination of these gonads disclosed right ovotestis and left ovary. Case 2. A 28 year-o l d male was evaluated at our clinic because of two year's sterility and hypospadiasis. At testicular biopsy, an ovoid structure was found in the left scrotum instead of a testicle. Histological examination of this ovoid structure revealed ovarian tissue. The right scrotal gonad was proved to be a testicle on microscopic examination. Sexchromatin pattern was male. Chromosomal analysis showed that the patient was represented by the cells with 46 chromosomes, the sex chromosome constitution being an XX. These two cases of true hermaphroditism were added to 35 cases so f a r reported in Japan.