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タイトル: | 尿路腫瘍とホルモン環境IV胸腺と尿路腫瘍 |
その他のタイトル: | Tumors of the Urinary Tract and the Hormonal Environments. IV : Thymus and Tumors of the Urinary Tract. |
著者: | 石部, 知行 福重, 満 竹中, 生昌 大野, 文夫 平山, 多秋 |
著者名の別形: | ISHIBE, Tomoyuki FUKUSHIGE, Mitsuru TAKENAKA, Ikumasa OONO, Fumio HIRAYAMA, Masaaki |
キーワード: | 17-Ketosteroids Adrenal Cortex Hormones Adrenocorticotropic Hormone Blood Chemical Analysis Eosinophils Gonadotropins Leukocyte Count Neoplasms, Experimental Physiology Prostatic Neoplasms Rabbits Rats Research Surgical Procedures, Operative Thymectomy Thymus Gland Urine CORTICOTROPIN EXPERIMENTAL LAB STUDY SURGERY, OPERATIVE |
発行日: | Jun-1964 |
出版者: | 京都大学医学部泌尿器科学教室 |
誌名: | 泌尿器科紀要 |
巻: | 10 |
号: | 6 |
開始ページ: | 331 |
終了ページ: | 337 |
抄録: | Investigations were carried out on the hormonal env i ronments in cases of the urinary tract tumors especially in cancer of the prostate with a reference to the thymus. 1. Following administration of the thymic agent, decreases in eo s inphile leukocyte count of the peripheral blood and excretions of the urinary total 17 KS and the urinary total 17 OHCS and a increase in the urinary gonadotropin were observed. 2. Following administration of the thymic agent, a transien t aggravation in reactibility against ACTH-Z was observed in patients with cancer of the prostate. 3. In male rats of the Wistar strain, participation of the thy m us to the prostate was investigated by means of extirpation of the thymus or administration of thymic agent. In both instances no remarkable change was recognized even though a tendency of decrease in the weight of the prostate and a suppressive effect to the adrenal glands were seen after administration of thymic agent. 4. In transplantation e xperiments of cancer tissue of the prostate into the anterior eye chamber of rabbit, a benefical result in growth of the transplanted graft was observed in thymectomized rabbits. These result s suggested us that administration of thymic agent can produce anti-male hormone effect though it is weak, and lead us to postulate that the administration of thymic agent to patients with cancer of the prostate should be done with a sufficient care because the administration made changes in reactibility against ACTH and increase in urinary gonadotropin excretion. |
URI: | http://hdl.handle.net/2433/112568 |
PubMed ID: | 14176873 |
出現コレクション: | Vol.10 No.6 |
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