前立腺偶発癌の頻度と予後に関する臨床病理学的研究(予報)

Abstract

前立腺肥大症の診断のもとに被膜下摘除術が行なわれた96例の摘出標本を対象に, step-section法による病理学的検索を行った.1) 96例中21例に偶発癌を認めた.2)摘出前立腺重量が重いほど, 高年齢であるほど偶発癌の合併率が高く, ある程度の関係があるように思われた.3)癌組織は標本外縁より3 mm以内に少なくとも一部が存在していた.4)癌占有体積が大きな偶発癌では組織学的悪性度が高い傾向がみられた.5)偶発癌の組織学的悪性度と予後との間に明らかな関係は認められなかった

To investigate the relationship between some clinico-pathological features of incidental prostatic carcinoma and its prognosis, totally 96 consecutive cases with simple prostatectomy from 1968 to 1973 under the diagnosis of prostatic hypertrophy were examined by the 3 mm step-section technique. Twenty-one cases (21.9%) of incidental carcinoma were detected histologically. The age of the patients with or without prostatic carcinoma ranged from 59 to 81 years old, 72.0 years old on the average, and from 54 to 87 years old, 69.9 years old on the average, respectively. The weight of the specimen varied from 7 to 84 grams, 32.4 g on the average, for the patients with carcinoma, and 10 to 64 grams, 29.7 g on the average, for the patients without carcinoma. Fifteen of 21 cases showed well differentiated carcinoma. None of the Japanese histological differentiation, Gleason's classification and volume of carcinoma presumably affected the survival of the patients.