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タイトル: | 腎癌を合併したvon Hippel-Lindau病の1症例とその家系 - 自験例と本邦報告15例の臨床的検討 - |
その他のタイトル: | A family of von Hippel-Lindau disease with renal cell carcinoma--case report and review of the literature |
著者: | 伊藤, 文夫 宇田, 光夫 東間, 紘 |
著者名の別形: | Ito, Fumio Uda, Mitsuo Toma, Hiroshi |
キーワード: | von Hippel-Lindau disease Renal cell carcinoma |
発行日: | Feb-1991 |
出版者: | 泌尿器科紀要刊行会 |
誌名: | 泌尿器科紀要 |
巻: | 37 |
号: | 2 |
開始ページ: | 157 |
終了ページ: | 162 |
抄録: | We report a 63-year-old woman with renal cell carcinoma associated with von Hippel-Lindau disease. The patient was referred to the department of neurosurgery at our hospital, complaining of gait disturbance. There was a history of retinal hemangioma. After further examination, von Hippel-Lindau disease was the conclusion with evidence of cerebellar hemangioblastoma. An abdominal CT-scan and arteriography revealed multiple hypervascular tumors in the right kidney, but not in the left. She underwent a right radical nephrectomy and lymphadenectomy 2 months after resection of a brain tumor. Von Hippel-Lindau disease is generally recognized as an autosomal-dominant inherited disorder. The patient had a positive family history, seen in both her younger brother and son. Both were diagnosed with renal cell carcinoma with central nervous system involvement before any sign of disease was found in the patient. Twenty one cases of von Hippel-Lindau disease associated with renal tumors have been reported in the Japanese literature. The clinical findings of these cases are discussed. |
URI: | http://hdl.handle.net/2433/117112 |
PubMed ID: | 2048495 |
出現コレクション: | Vol.37 No.2 |
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