市立静岡病院における尿路結石症の臨床的検討 --結石成分分析および尿中カルシウム,尿酸排泄量について--

Abstract

自然排石あるいは手術によって採取した尿路結石216個(205症例)につき赤外線分光分析をおこない, 結石分析を施行した尿路結石患者61例を対象として尿中カルシウムおよび尿酸値測定を行なった.その結果, 成分別で本来感染結石と考えられるリン酸マグネシウムアンモニウム結石のなかにも高カルシウム尿症や高尿酸尿症を3例に認めた.発生部位別にみると, 下部尿路結石にも高カルシウム尿症を2例認めた.2例ともカルシウム結石症例であった.単発・多発別にみると, やはり単発例と比較して多発例に多く異常を認めた

Stone analysis was performed for 216 urinary calculi which were obtained from 205 patients in our hospital from January, 1980 to June, 1984. The results revealed 161 calcium stones, 21 uric acid stones, 19 struvite stones, 2 cystine stones and 13 others. Sixty one of the 205 patients (male 44, female 17) and 19 controls (male 11, female 8) were investigated for 24-hour urine calcium and uric acid. Forty seven of the patients had calcium stones, 7 of the patients had uric acid stones and 7 of the patients had struvite stones. The mean 24-hour urine calcium level was 146.8 +/- 76.5 mg/day for the male controls and 139.1 +/- 69.9 mg/day for the female controls. The mean 24-hour urine uric acid level was 528.1 +/- 132.6 mg/day for the male controls and 362.0 +/- 135.2 mg/day for the female controls. The mean 24-hour urine calcium level for the male calcium-stone group was 214.6 +/- 96.8 mg/day, and it was significantly higher than that for the male controls (p less than 0.05). The 24-hour urine analysis revealed abnormalities in 17 urolithiasis patients (27.9%) including hypercalciuria in 11 patients (18.0%) and hyperuricosuria in 9 patients (14.1%).