ダウンロード数: 323
このアイテムのファイル:
ファイル | 記述 | サイズ | フォーマット | |
---|---|---|---|---|
gen-2012-0123.pdf | 319.68 kB | Adobe PDF | 見る/開く |
タイトル: | In situ hybridization analysis of gibbon chromosomes suggests that amplification of alpha satellite DNA in the telomere region is confined to two of the four genera. |
著者: | Baicharoen, Sudarath Arsaithamkul, Visit Hirai, Yuriko Hara, Toru Koga, Akihiko Hirai, Hirohisa |
著者名の別形: | 平井, 啓久 |
キーワード: | heterochromatin telomere alpha satellite DNA gibbon hominoids |
発行日: | 9-Nov-2012 |
出版者: | NRC Research Press |
誌名: | Genome |
巻: | 55 |
号: | 11 |
開始ページ: | 809 |
終了ページ: | 812 |
抄録: | The siamang (Symphalangus syndactylus), a species of the family Hylobatidae (gibbons), carries large blocks of constitutive heterochromatin in the telomere region of chromosomes. We recently found that alpha satellite DNA constitutes these heterochromatin blocks as a main component. Alpha satellite DNA, tandem repeat sequences of 171-bp repeat units, is a major component of centromeres in primates. In addition to the siamang, the white-cheeked gibbon (Nomascus leucogenys) was previously found to carry the alpha satellite DNA in the telomere region, although not as large a scale as the siamang. Gibbons comprise four genera: Hoolock, Hylobates, Nomascus, and Symphalangus. Here, we report that the amplification of alpha satellite DNA in the telomere region is probably confined to two genera: Nomascus and Symphalangus. We examined one species of Hoolock and four species of Hylobates and obtained evidence against such an amplification event in these species. The phylogenetic relationship of the four gibbon genera remains unclear. One simple explanation for the current distribution of the telomere region alpha satellite DNA would be that Nomascus and Symphalangus are relatively closely related and the amplification occurred in their common ancestor. |
著作権等: | © 2012 NRC Research Press この論文は著者最終稿です。内容が印刷版と異なることがありますので、引用の際には出版社版をご確認ご利用ください。This is the Accepted Author Manuscript. Please cite only the published version. |
URI: | http://hdl.handle.net/2433/166331 |
DOI(出版社版): | 10.1139/gen-2012-0123 |
PubMed ID: | 23199575 |
出現コレクション: | 学術雑誌掲載論文等 |
このリポジトリに保管されているアイテムはすべて著作権により保護されています。