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| ファイル | 記述 | サイズ | フォーマット | |
|---|---|---|---|---|
| jvms.15-0213.pdf | 291.16 kB | Adobe PDF | 見る/開く |
| タイトル: | <i>In vitro</i> host range of feline morbillivirus |
| 著者: | SAKAGUCHI, Shoichi KOIDE, Rie MIYAZAWA, Takayuki   |
| 著者名の別形: | 坂口, 翔一 小出, りえ 宮沢, 孝幸 |
| キーワード: | cat cell tropism cross-species transmission feline morbillivirus host range |
| 発行日: | 2015 |
| 出版者: | Japanese Society of Veterinary Science |
| 誌名: | The Journal of veterinary medical science |
| 巻: | 77 |
| 号: | 11 |
| 開始ページ: | 1485 |
| 終了ページ: | 1487 |
| 抄録: | Feline morbillivirus (FmoPV) is an emerging virus in cats, which is associated with tubulointerstitial nephritis. To study the in vitro host range of FmoPV, we inoculated FmoPV strain SS1 to 32 cell lines originated from 13 species and cultured for 2 weeks, followed by RNA extraction and reverse-transcription-polymerase chain reaction for FmoPV detection. As a result, only cell lines derived from cats and African green monkeys were susceptible to FmoPV. FmoPV infects diverse feline cell lines: epithelial, fibroblastic, lymphoid and glial cells. These results indicate that the receptor (s) for FmoPV are ubiquitously expressed in cats. No infectivity of FmoPV was observed in human cell lines, which suggests least threatening of cross-species transmission of FmoPV from cats to humans. |
| 著作権等: | ©2015 The Japanese Society of Veterinary Science This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial No Derivatives (by-nc-nd) License <http://creativecommons.org/licenses/by-nc-nd/3.0/>. |
| URI: | http://hdl.handle.net/2433/219558 |
| DOI(出版社版): | 10.1292/jvms.15-0213 |
| PubMed ID: | 26027844 |
| 出現コレクション: | 学術雑誌掲載論文等 |
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