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タイトル: | Middle cerebral artery-peak systolic velocity in dizygotic twins with anti-E alloimmunization. |
著者: | Satake, Yumiko Sato, Yukiyasu Matsumura, Noriomi Tatsumi, Keiji Fujiwara, Hiroshi Konishi, Ikuo |
著者名の別形: | 佐藤, 幸保 |
キーワード: | alloimmunization amniocentesis Doppler hemolytic disease of newborn |
発行日: | 11-Oct-2010 |
出版者: | wiley |
誌名: | The journal of obstetrics and gynaecology research |
巻: | 36 |
号: | 6 |
開始ページ: | 1236 |
終了ページ: | 1239 |
抄録: | Middle cerebral artery-peak systolic velocity (MCA-PSV) has been reported to predict fetal anemia with similar accuracy as amniotic ΔOD450 assay. Alloimmunized dizygotic twin pregnancy allows us to compare anemic and non-anemic twins in the same intrauterine environment. We herein present a case of Rh (E)-incompatible dizygotic twin pregnancy, where MCA-PSV could precisely detect the anemia in one of the twins. A 36-year-old woman, whose previous child required exchange transfusion due to hemolytic anemia of newborn (HFDN), conceived twins after in vitro fertilization-embryo transfer. At 24 weeks' gestation, MCA-PSV of twin A and twin B were 23.9 cm/s (0.8 multiples of median; MoM) and 30.7 cm/s (1.0 MoM), respectively. At 31 weeks' gestation, MCA-PSV values of both twins were sharply elevated to nearly 1.4 MoM. Thereafter, MCA-PSV of twin A fell to 1.0 MoM, whereas MCA-PSV of twin B exceeded 1.5 MoM at 34 weeks' gestation. Development of fetal anemia was suspected and emergency cesarean section was performed. Twin B showed moderate anemia with positive direct Coombs' test and was diagnosed as HFDN due to anti-E alloimmunization. Twin B required phototherapy and red cell transfusion, but exchange transfusion was safely obviated. |
著作権等: | This is the peer reviewed version of the following article: Satake, Y., Sato, Y., Matsumura, N., Tatsumi, K., Fujiwara, H. and Konishi, I. (2010), Middle cerebral artery-peak systolic velocity in dizygotic twins with anti-E alloimmunization. Journal of Obstetrics and Gynaecology Research, 36: 1236–1239, which has been published in final form at http://dx.doi.org/10.1111/j.1447-0756.2010.01314.x この論文は出版社版でありません。引用の際には出版社版をご確認ご利用ください。 This is not the published version. Please cite only the published version. |
URI: | http://hdl.handle.net/2433/197588 |
DOI(出版社版): | 10.1111/j.1447-0756.2010.01314.x |
PubMed ID: | 21040209 |
出現コレクション: | 学術雑誌掲載論文等 |
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