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タイトル: | Persistent frequent subclinical seizures and memory impairment after clinical remission in smoldering limbic encephalitis. |
著者: | Kanazawa, Kyoko Matsumoto, Riki https://orcid.org/0000-0003-3985-9210 (unconfirmed) Shimotake, Akihiro Kinoshita, Masako Otsuka, Akiko Watanabe, Osamu Tanaka, Keiko Takahashi, Ryosuke https://orcid.org/0000-0002-1407-9640 (unconfirmed) Ikeda, Akio https://orcid.org/0000-0002-0790-2598 (unconfirmed) |
著者名の別形: | 金澤, 恭子 |
キーワード: | EEG seizure pattern memory impairment smoldering limbic encephalitis voltage-gated potassium-channel complex antibody antineuronal antibody epilepsy |
発行日: | Sep-2014 |
出版者: | John Libbey Eurotext |
誌名: | Epileptic disorders |
巻: | 16 |
号: | 3 |
開始ページ: | 312 |
終了ページ: | 317 |
抄録: | Aim. To delineate a possible correlation between clinical course and EEG abnormalities in non-infectious “smoldering” limbic encephalitis. Methods. Long-term clinical data, including video-EEG monitoring records, were analysed in two patients. Results. The two patients were positive for anti-voltage-gated potassium channel complex antibody and unspecified antineuronal antibody, respectively. The latter patient had small cell lung carcinoma. Both patients had memory impairment and clinical seizures. EEG showed frequent subclinical seizure patterns in the bilateral temporal regions. Subclinical seizure patterns and memory impairment persisted over one to two years after clinical seizure remission. Therapy (prednisolone and chemoradiation in the two patients, respectively) resulted in decreased occurrence of subclinical seizure patterns and memory improvement. Conclusions. EEG seizure patterns may persist years after clinical seizure remission in “smoldering” limbic encephalitis and lead to memory impairment. |
著作権等: | © John Libbey Eurotext 許諾条件により本文ファイルは2015-10-01に公開. |
URI: | http://hdl.handle.net/2433/198597 |
DOI(出版社版): | 10.1684/epd.2014.0664 |
PubMed ID: | 25036726 |
出現コレクション: | 学術雑誌掲載論文等 |
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