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タイトル: Formation of the circle of Willis during human embryonic development
著者: Takakuwa, Tetsuya  kyouindb  KAKEN_id  orcid https://orcid.org/0000-0002-9660-9384 (unconfirmed)
Koike, Teppei
Muranaka, Taiga
Uwabe, Chigako
Yamada, Shigehito  kyouindb  KAKEN_id  orcid https://orcid.org/0000-0002-8194-6927 (unconfirmed)
著者名の別形: 高桑, 徹也
山田, 重人
キーワード: circle of Willis
human embryo
three-dimensional reconstruction
発行日: 1-Sep-2016
出版者: Wiley-Blackwell
誌名: Congenital Anomalies
巻: 56
号: 5
開始ページ: 233
終了ページ: 236
抄録: The circle of Willis (CW) is a circulatory anastomosis that supplies blood to the brain and adjacent structures. We examined the timing of formation of CW in 20 Japanese human embryo samples by using 3-dimensional reconstruction of serial histological sections. The CW was closed in 1 (n = 6), 2 (n = 8), 2 (n = 3) and 2 (n = 3) samples at Carnegie stages 20, 21, 22, and 23, respectively. The CW was unclosed in 13 samples (unclosed at ACOM alone, 6 samples; ACOM and bilateral P1, 4; left PCOM and right P1, 1; right PCOM and right P1, 1; ACOM and left PCOM, 1). It was difficult to predict whether the circle would close during further development, as such variations frequently exist in adults.
著作権等: This is the accepted version of the following article: [Takakuwa, T., Koike, T., Muranaka, T., Uwabe, C., and Yamada, S. (2016) Formation of the circle of Willis during human embryonic development. Congenital Anomalies, 56: 233–236.], which has been published in final form at http://dx.doi.org/10.1111/cga.12165. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Self-Archiving.
The full-text file will be made open to the public on 1 September 2017 in accordance with publisher's 'Terms and Conditions for Self-Archiving'.
This is not the published version. Please cite only the published version.
この論文は出版社版でありません。引用の際には出版社版をご確認ご利用ください。
URI: http://hdl.handle.net/2433/216971
DOI(出版社版): 10.1111/cga.12165
PubMed ID: 27037515
出現コレクション:学術雑誌掲載論文等

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