術前の尿細胞診より疑われた膀胱小細胞癌の1例

Abstract

A 70-year-old man complaining of fever and chills was admitted to our hospital. A computerized tomographyscan revealed a bladder tumor (cT3bN0M0), and urinarycy tologydemonstrated neuroendocrine carcinoma. Prostate specific antigen (PSA) was 4.089 ng/ml and human cytokeratin 19 fragment (CYFRA 21-1) was 3.8 ng/ml. He underwent transurethral resection of bladder tumor and needle biopsyof the prostate. Pathological examination demonstrated small cell carcinoma in the bladder tumor specimen and well differentiated adenocarcinoma (cT1c) with a Gleason score of 3＋4 in the prostatic specimen. He underwent cystoprostatectomy with bilateral cutaneous ureterostomy. He did not receive adjuvant chemotherapybecause of the poor postoperative systemic condition and he died of acute myocardial infarction 5 months later.