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DCフィールド | 値 | 言語 |
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dc.contributor.author | 岩城, 秀出洙 | ja |
dc.contributor.author | 成田, 充弘 | ja |
dc.contributor.author | 曽我, 弘樹 | ja |
dc.contributor.author | 坂野, 祐司 | ja |
dc.contributor.author | 小西, 平 | ja |
dc.contributor.author | 岡田, 裕作 | ja |
dc.contributor.alternative | Iwaki, Hideaki | en |
dc.contributor.alternative | Narita, Mitsuhiro | en |
dc.contributor.alternative | Soga, Hiroki | en |
dc.contributor.alternative | Sakano, Yuji | en |
dc.contributor.alternative | Konishi, Taira | en |
dc.contributor.alternative | Okada, Yusaku | en |
dc.date.accessioned | 2010-05-07T02:21:10Z | - |
dc.date.available | 2010-05-07T02:21:10Z | - |
dc.date.issued | 2010-04 | - |
dc.identifier.issn | 0018-1994 | - |
dc.identifier.uri | http://hdl.handle.net/2433/109922 | - |
dc.description.abstract | Nocturnal urinary frequency is a predominant complaint among males presenting with benign prostatic hyperplasia (BPH), which markedly impacts quality of life (QOL) and often causes sleep disturbance. We studied the efficacy of naftopidil an alpha 1-adrenoreceptor antagonist used for treatment of BPH for improvement of nocturia and consequent sleep disturbance. Twenty-five patients diagnosed with BPH were administered daily oral doses of naftopidil (50 or 75 mg/day) for eight weeks. The symptoms were assessed quantitatively using the following criteria : International Prostate Symptoms Score (I-PSS), QOL index, frequency volume chart, and Pittsburgh Sleep Quality Index (PSQI). After treatment, the mean±SD of total I-PSS and nocturia decreased from 16.9±5.2 to 10.3±4.9 (p<0.001) and 3.5±1.2 to 2.3±1.3 (p< 0.001), respectively. In addition, all categories of storage symptoms in I-PSS were also significantly improved. PSQI results were obtained in 21 of the 25 patients, and decreased from 6.4±4.2 to 5.3±3.5 (p=0.026) (normal range : less than 5.5). This is the first report of a quantitative analysis of the effect of naftopidil on sleep quality in BPH patients. In conclusion, naftopidil appears to be an effective agent not only for nocturia and other urinary storage symptoms, but also for improving the quality of sleep. | en |
dc.format.mimetype | application/pdf | - |
dc.language.iso | jpn | - |
dc.publisher | 泌尿器科紀要刊行会 | ja |
dc.rights | 許諾条件により本文は2011-05-01に公開 | ja |
dc.subject | Benign prostatic hyperplasia | en |
dc.subject | Naftopidil | en |
dc.subject | Nocturia | en |
dc.subject | Sleep disturbance | en |
dc.subject | Pittsburgh sleep quality index | en |
dc.subject.ndc | 494.9 | - |
dc.title | 前立腺肥大症患者の夜間頻尿と睡眠障害に対するナフトピジルの有用性について | ja |
dc.title.alternative | The Efficacy of Naftopidil for Nocturia and Consequent Sleep Disturbance in Patients with Benign Prostatic Hyperplasia | en |
dc.type | departmental bulletin paper | - |
dc.type.niitype | Departmental Bulletin Paper | - |
dc.identifier.ncid | AN00208315 | - |
dc.identifier.jtitle | 泌尿器科紀要 | ja |
dc.identifier.volume | 56 | - |
dc.identifier.issue | 4 | - |
dc.identifier.spage | 209 | - |
dc.identifier.epage | 213 | - |
dc.textversion | publisher | - |
dc.sortkey | 03 | - |
dc.address | 豊郷病院泌尿器科 | ja |
dc.address | 滋賀医科大学泌尿器科 | ja |
dc.address | 豊郷病院泌尿器科 | ja |
dc.address | 社会保険滋賀病院泌尿器科 | ja |
dc.address | 医療法人輝生会小西医院 | ja |
dc.address | 滋賀医科大学泌尿器科 | ja |
dc.startdate.bitstreamsavailable | 2011-05-01 | - |
dc.address.alternative | The Department of Urology, Toyosato Hospital | en |
dc.address.alternative | The Department of Urology, Shiga University of Medical Science | en |
dc.address.alternative | The Department of Urology, Toyosato Hospital | en |
dc.address.alternative | The Department of Urology, Shiga Social Insurance Hospital | en |
dc.address.alternative | Konishi Clinic | en |
dc.address.alternative | The Department of Urology, Shiga University of Medical Science | en |
dc.identifier.pmid | 20448444 | - |
dcterms.accessRights | open access | - |
dc.identifier.pissn | 0018-1994 | - |
dc.identifier.jtitle-alternative | Acta urologica Japonica | la |
dc.identifier.jtitle-alternative | Hinyokika Kiyo | en |
出現コレクション: | Vol.56 No.4 |
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