尿路カンジダ症の臨床竝びに実験的研究 II実験篇

Abstract

The urine and excretions of the urinary tract were cultured in 45 cases of the genito-urinary diseases showing resistanse against the treatments with various antibiotics, and in 4 of them, candida were isolated. Intracutaneous injection was carried out with the filtrated solutions of candida albicans isolated from one case, in 103 persons. The positivity of this skin reactions were as follows; on 50 of sound persons as the control, 26 % were positive, while in 46 of the trichophytiasis, 45 %; in 5 of urethritis simplex, 80 %; penicillin allergy, , urinary candidiasis, every 100 %. Living candida albicans isolated from one case experienced by ourselves, was injected to the guinea pigs, which had been dead for one week after the applications and candida had been cultured from the seminal vesicles and bladders of these animals. It was recognized that lungs, hearts, livers, spleens, kidneys, and bladders of these animals had been attacked on foreign body reactions and Some degenerations by candida albicans.