腎結核に於けるアミノ酸の研究(ペーパークロマトグラフィーに依る) 第3編:腎結核組織内遊離アミノ酸の組織化学的分布(臨床実験並びに動物実験成績)

Abstract

The author previously described some notes of clinical and experimental results of distribution of free amino acids in the tuberculous renal tissue by use of paper partition chromatography, and describes the histochemical distribution of amino acids at renal tuberculous focus in the present report. The distribution of free amino acids at the renal tuberculous focus was histochemically investigated in ten clinical cases and ten rabbits by Serra's method, and disclosed the following facts. 1. In t h e pathological tissue, the state of free amino acids varies by the degree of tuberculous pathological findings. 2. The amino acid re a ction appears intensively in the wall of the tuberculous cavity, in the caseous knot, in the non-caseous knot and in the impaired capillary wall. 3. The reaction of the caseous substance in which some cases showed a positive reaction is in general weak. 4. There are n o significant difference in the tuberculous changes of the vascular wall and also of Bowman's capsula.